(E)-2-nitro-3-m-tolylallyl acetate

Base Information

• Chemical Name: (E)-2-nitro-3-m-tolylallyl acetate
• CAS No.: 1201183-55-2
• Molecular Formula: C₁₂H₁₃NO₄
• Molecular Weight: 235.24
• Mol file: 1201183-55-2.mol

Synonyms:(E)-2-nitro-3-m-tolylallyl acetate

Chemical Property of (E)-2-nitro-3-m-tolylallyl acetate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (E)-2-nitro-3-m-tolylallyl acetate

There total 1 articles about (E)-2-nitro-3-m-tolylallyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

(E)-2-nitro-3-m-tolylprop-2-en-1-ol (1201183-74-5) + acetyl chloride (75-36-5) → (E)-2-nitro-3-m-tolylallyl acetate (1201183-55-2,114430-11-4)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; in air;

DOI:10.1002/chem.200900696

Reference yield: 88.0%

1H-indol-4-ol (2380-94-1) + (E)-2-nitro-3-m-tolylallyl acetate (1201183-55-2,114430-11-4) → (3S,4R)-4-(m-tolyl)-3-nitro-2,3,4,7-tetrahydropyrano[2,3-e]indole

Guidance literature:

With dipotassium hydrogenphosphate; 3-((3,5-bis(trifluoromethyl)phenyl)amino)-4-(((S)-(6-methoxyquinoline-4-yl))((1S,2S,4S,5R-5-vinylquinuclidine-2-yl)methyl)amino)cyclobutan-3-ene-1,2-dione; In dichloromethane; at 50 ℃; for 24h; enantioselective reaction; Molecular sieve;

DOI:10.1021/acs.orglett.8b00503

Reference yield:

1H-indol-4-ol (2380-94-1) + (E)-2-nitro-3-m-tolylallyl acetate (1201183-55-2,114430-11-4) → 4-(m-tolyl)-3-nitro-2,3,4,7-tetrahydropyrano[2,3-e]indole

Guidance literature:

With dipotassium hydrogenphosphate; (3-((3,5-bis(trifluoromethyl)phenyl)amino)-4-((2-(dimethylamino)ethyl)amino)-cyclobut-3-en-1,2-dione); In 1,2-dichloro-ethane; at 80 ℃; for 24h; Sealed tube;

DOI:10.1021/acs.orglett.8b00503

upstream raw materials:

(E)-2-nitro-3-m-tolylprop-2-en-1-ol

acetyl chloride