4-Benzoyl-l-phenylalanine

Base Information

Chemical Name:4-Benzoyl-l-phenylalanine
CAS No.:104504-45-2
Molecular Formula:C16H15NO3
Molecular Weight:269.3
Hs Code.:29225090
UNII:9RU6KQ9WYD
DSSTox Substance ID:DTXSID20909021
Nikkaji Number:J632.372C
Wikidata:Q27097586
Mol file:104504-45-2.mol

Synonyms:4-benzoylphenylalanine;BzF amino acid;p-benzoyl-L-phenylalanine;p-benzoylphenylalanine;p-Bpa amino acid;pBpa amino acid

Suppliers and Price of 4-Benzoyl-l-phenylalanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
H-p-Bz-Phe-OH
1 g
$ 152.00

SynQuest Laboratories
H-p-Bz-Phe-OH
5 g
$ 472.00

SynQuest Laboratories
H-p-Bz-Phe-OH
10 g
$ 856.00

Labseeker
L-4-Benzoylphenylalanine 98
50g
$ 3483.00

Labseeker
L-4-Benzoylphenylalanine 98
100g
$ 5250.00

Iris Biotech GmbH
H-L-Bpa-OH
25 g
$ 3820.50

Iris Biotech GmbH
H-L-Bpa-OH
5 g
$ 1039.50

Iris Biotech GmbH
H-L-Bpa-OH
1 g
$ 364.50

Frontier Specialty Chemicals
4-Benzoyl-L-phenylalanine 95%
1g
$ 221.00

Frontier Specialty Chemicals
4-Benzoyl-L-phenylalanine 95%
250mg
$ 74.00

Total 77 raw suppliers

Chemical Property of 4-Benzoyl-l-phenylalanine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.616
Boiling Point:467.605 °C at 760 mmHg
PKA:2.16±0.10(Predicted)
Flash Point:236.599 °C
PSA：80.39000
Density:1.249 g/cm³
LogP:2.57230
Storage Temp.:-15°C
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:269.10519334
Heavy Atom Count:20
Complexity:342

Purity/Quality:

97% ^*data from raw suppliers

H-p-Bz-Phe-OH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)CC(C(=O)O)N
Isomeric SMILES:C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)C[C@@H](C(=O)O)N
Recent ClinicalTrials:Study to Assess the Safety, Tolerability and Pharmacokinetic Profile of PBF-999 'After Multiple Oral Doses' in Healthy Volunteers
Uses 4-Benzoyl-L-phenylalanine is a photoreactive amino acid which can easily be incorporated into a peptide by solid-phase synthesis and finds application as phtolabel. It is an important raw material as well as an intermediate in organic synthesis.

Technology Process of 4-Benzoyl-l-phenylalanine

There total 4 articles about 4-Benzoyl-l-phenylalanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 98-88-4
benzoyl chloride

: 104504-45-2
p-Benzoyl-DL-Phenylalanine

Guidance literature:: With trifluorormethanesulfonic acid; at 0 - 20 ℃; for 12h;
DOI:10.3390/molecules18078393

Reference yield:

: C₁₉H₁₆F₃NO₄

: 104504-45-2
p-Benzoyl-DL-Phenylalanine

Guidance literature:: With sodium hydroxide; In methanol; water; acetonitrile; at 20 ℃;
DOI:10.3987/COM-13-12815

Reference yield:

: 23635-30-5
(S)-(-)-methyl N-(trifluoroacetyl)phenylalaninate

: 98-88-4
benzoyl chloride

: 104504-45-2
p-Benzoyl-DL-Phenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / 0 °C

1.2: 10 h / 20 °C

2.1: sodium hydroxide / methanol; water; acetonitrile / 20 °C

With trifluorormethanesulfonic acid; sodium hydroxide; In methanol; water; acetonitrile; 1.2: |Friedel-Crafts Acylation;
DOI:10.3987/COM-13-12815