methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside

Base Information

• Chemical Name: methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside
• CAS No.: 873093-23-3
• Molecular Formula: C₆₁H₆₅NO₁₁
• Molecular Weight: 988.187
• Mol file: 873093-23-3.mol

Synonyms:methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside

Chemical Property of methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside

There total 8 articles about methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4,5-dihydrothiazol-2-yl 3,4,6-tri-O-benzyl-2-O-picolyl-1-thio-β-D-glucopyranoside (876034-57-0) + methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) → methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside (873093-23-3)

Guidance literature:

4,5-dihydrothiazol-2-yl 3,4,6-tri-O-benzyl-2-O-picolyl-1-thio-β-D-glucopyranoside; methyl 2,3,4-tri-O-benzyl-D-glucopyranoside; In DCE; for 1h; Molecular sieve; Inert atmosphere;

With trifluorormethanesulfonic acid; In DCE; at 20 ℃; Inert atmosphere;

With copper(II) bis(trifluoromethanesulfonate); In DCE; at 40 ℃; for 16h; Inert atmosphere;

DOI:10.1021/jo801551r

Reference yield: 84.0%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + C35H35Cl3N2O6 → methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside (873093-23-3)

Guidance literature:

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside; C₃₅H₃₅Cl₃N₂O₆; In DCE; for 1h; Molecular sieve; Inert atmosphere;

With triethylsilyl trifluoromethyl sulfonate; In DCE; at 40 ℃; for 16h; Inert atmosphere;

DOI:10.1021/jo801551r

Reference yield: 83.0%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + ethyl 3,4,6-tri-O-benzyl-2-O-picolinyl-1-thio-β-D-glucopyranoside (1083195-76-9) → methyl 2,3,4-tri-O-benzyl-6-O-(3,4,6-tri-O-benzyl-2-O-picolinyl-β-D-glucopyranosyl)-α-D-glucopyranoside (873093-23-3)

Guidance literature:

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside; ethyl 3,4,6-tri-O-benzyl-2-O-picolinyl-1-thio-β-D-glucopyranoside; In 1,2-dichloro-ethane; for 1h; Molecular sieve; Inert atmosphere;

With dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane; at -30 - 42 ℃; for 21h;

DOI:10.1021/ja307355n

upstream raw materials:

4,5-dihydrothiazol-2-yl 3,4,6-tri-O-benzyl-2-O-picolyl-1-thio-β-D-glucopyranoside

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside

3,4,6-tri-O-benzyl-1,2-O-[1-(ethylsulfanyl)ethylidene]-α-D-glucopyranose

4,5-dihydrothiazol-2-yl 3,4,6-tri-O-benzyl-1-thio-β-D-glucopyranoside

Downstream raw materials:

methyl 6-O-(β-D-glucopyranosyl)-α-D-glucopyranoside