1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Base Information

Chemical Name:1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate
CAS No.:1258847-18-5
Molecular Formula:C₂₃H₃₁NO₅
Molecular Weight:401.503
Hs Code.:

Synonyms:1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Suppliers and Price of 1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

There total 6 articles about 1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1236206-73-7
C₁₃H₂₁ClO₃

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 1258847-18-5
1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Guidance literature:: With n-butyllithium; In tetrahydrofuran; hexane;
DOI:10.1016/j.tetlet.2010.04.109

Reference yield:

: 1353777-80-6
1-[4-(1-hydroxycyclopropyl)butyl]cyclopropyl pivaloate

: 1258847-18-5
1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Guidance literature:: Multi-step reaction with 3 steps

1.1: [bis(acetoxy)iodo]benzene / 0.5 h / Cooling

1.2: Reflux

2.1: thionyl chloride / tetrachloromethane / 3 h / Reflux

3.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -78 °C

3.2: 0.5 h / -78 °C

With n-butyllithium; thionyl chloride; [bis(acetoxy)iodo]benzene; In tetrahydrofuran; tetrachloromethane; hexane;
DOI:10.1134/S1070428011110029

Reference yield:

: 207298-22-4
1,4-bis(1-hydroxycyclopropyl)butane

: 1258847-18-5
1-{5-[(4S)-4-benzyl-2-oxooxazolidin-3-yl]-5-oxopentyl}cyclopropyl pivaloate

Guidance literature:: Multi-step reaction with 4 steps

1.1: pyridine; dmap; pivaloyl chloride / 0 - 5 °C

2.1: [bis(acetoxy)iodo]benzene / 0.5 h / Cooling

2.2: Reflux

3.1: thionyl chloride / tetrachloromethane / 3 h / Reflux

4.1: n-butyllithium / tetrahydrofuran; hexane / 0.08 h / -78 °C

4.2: 0.5 h / -78 °C

With pyridine; dmap; n-butyllithium; thionyl chloride; [bis(acetoxy)iodo]benzene; pivaloyl chloride; In tetrahydrofuran; tetrachloromethane; hexane;
DOI:10.1134/S1070428011110029