(R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide

Base Information

• Chemical Name: (R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide
• CAS No.: 420133-80-8
• Molecular Formula: C₉H₁₉NOS
• Molecular Weight: 189.322
• Mol file: 420133-80-8.mol

Synonyms:(R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide

Chemical Property of (R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide

There total 1 articles about (R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(R)-2-amino-3-methylbutanol (4276-09-9,473-75-6) + methyl 2-methylpropanedithioate (5874-02-2) → (R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide (420133-80-8)

Guidance literature:

With triethylamine; at 20 ℃; for 12h;

DOI:10.1016/S0957-4166(01)00481-5

Reference yield: 98.0%

(R)-N-[1-(hydroxymethyl)-2-methylpropyl]-2-methylpropanethioamide (420133-80-8) → (R)-2,4-diisopropyl-2-thiazoline (420134-18-5)

Guidance literature:

With methanesulfonyl chloride; triethylamine; In tetrahydrofuran; at 20 ℃; for 0.166667h;

DOI:10.1016/S0957-4166(01)00481-5

upstream raw materials:

(R)-2-amino-3-methylbutanol

methyl 2-methylpropanedithioate

Downstream raw materials:

(R)-2,4-diisopropyl-2-thiazoline