N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide

Base Information

• Chemical Name: N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide
• CAS No.: 331461-23-5
• Molecular Formula: C₁₂H₁₇N₃OS₂
• Molecular Weight: 283.418
• Mol file: 331461-23-5.mol

Synonyms:N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide

Chemical Property of N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

N-Cyclohexyl-2-(2-thienylcarbonyl)-1-hydrazinecarbothioamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide

There total 2 articles about N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

2-thienylhydrazide (2361-27-5) + isothiocyanatocyclohexane (1122-82-3) → N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide (331461-23-5)

Guidance literature:

at 80 ℃; for 12h;

DOI:10.1080/10426500801968136

Reference yield:

Ethyl thiophene-2-carboxylate (2810-04-0) → N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide (331461-23-5)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / Reflux

2: ethanol / 5 h / Reflux

With hydrazine hydrate; In ethanol;

DOI:10.1007/s00044-019-02442-1

Reference yield: 89.0%

N-cyclohexyl-2-(thiophene-2-carbonyl)hydrazinecarbothioamide (331461-23-5) → C12H15N3S2 (724701-83-1)

Guidance literature:

With sodium hydroxide; In water; for 2h; Reflux;

DOI:10.1080/10426500801968136

upstream raw materials:

2-thienylhydrazide

isothiocyanatocyclohexane

Ethyl thiophene-2-carboxylate

Downstream raw materials:

C₁₂H₁₅N₃S₂