O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate

Base Information

Chemical Name:O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate
CAS No.:118149-27-2
Molecular Formula:C₅₀H₅₁Cl₂N₄O₁₃PS₂
Molecular Weight:1081.99
Hs Code.:

Synonyms:O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate

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Chemical Property of O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate

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Technology Process of O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate

There total 19 articles about O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 129789-68-0
triethylammonium O-<5'-O-(4,4'-dimethoxytrityl)-thymidin-3'-yl> S-(2,4-dichlorobenzyl) phosphorodithioate

: 21090-30-2
3'-O-acetylthymidine

: 118149-27-2
O-[5'-O-(4,4'-dimethoxytrityl)thymidin-3'-yl] S-(2,4-dichlorobenzyl) O-(3'-O-acetylthymidin-5'-yl) phosphorodithioate

Guidance literature:: With 1-methyl-1H-imidazole; triisopropylbenzenesulfonylchloride; In dichloromethane; for 1.5h; Ambient temperature;
DOI:10.1016/S0040-4039(00)88887-5