(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Base Information

Chemical Name:(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide
CAS No.:866454-50-4
Molecular Formula:C₁₇H₂₅NO₄
Molecular Weight:307.39
Hs Code.:

Synonyms:(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Suppliers and Price of (2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

There total 7 articles about (2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

: 866454-49-1
3-methoxy-2-(4-methoxybenzyloxy)-5-methylhex-5-enoic acid (1-methoxy-2-phenylethyl)amide

: 866454-50-4
(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane;
DOI:10.1021/ol051396s

Reference yield:

: 3-methoxy-2-(4-methoxybenzyloxy)-5-methylhex-5-enal

: 866454-50-4
(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Guidance literature:: Multi-step reaction with 5 steps

1: 2-methyl-2-butene; aq. NaClO₂; NaH₂PO₄*H₂O / 2-methyl-propan-2-ol / 0.5 h / 20 °C

2: SOCl₂; Et₃N / CH₂Cl₂ / 2 h / 0 - 20 °C

3: Et₃N / CH₂Cl₂ / 4 h / 0 - 20 °C

4: 61 mg / NaBH₄ / ethanol / 2 h / 0 °C

5: 39 percent / DDQ / CH₂Cl₂

With sodium chlorite; sodium tetrahydroborate; sodium dihydrogenphosphate; thionyl chloride; 2-methyl-but-2-ene; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In ethanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ol051396s

Reference yield:

: 866454-55-9
3-methoxy-2-(4-methoxybenzyloxy)-5-methylhex-5-en-1-ol

: 866454-50-4
(2S,3R)-2-Hydroxy-3-methoxy-5-methyl-hex-5-enoic acid (1-methoxy-2-phenyl-ethyl)-amide

Guidance literature:: Multi-step reaction with 6 steps

1: SO₃*Py; DMSO; Et₃N / 0.33 h

2: 2-methyl-2-butene; aq. NaClO₂; NaH₂PO₄*H₂O / 2-methyl-propan-2-ol / 0.5 h / 20 °C

3: SOCl₂; Et₃N / CH₂Cl₂ / 2 h / 0 - 20 °C

4: Et₃N / CH₂Cl₂ / 4 h / 0 - 20 °C

5: 61 mg / NaBH₄ / ethanol / 2 h / 0 °C

6: 39 percent / DDQ / CH₂Cl₂

With sodium chlorite; sodium tetrahydroborate; sodium dihydrogenphosphate; thionyl chloride; 2-methyl-but-2-ene; pyridine-SO₃ complex; dimethyl sulfoxide; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In ethanol; dichloromethane; tert-butyl alcohol;
DOI:10.1021/ol051396s