tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
CAS No.:183852-65-5
Molecular Formula:C12H22N2O4
Molecular Weight:258.3141
Hs Code.:
Mol file:183852-65-5.mol

Synonyms:2-Methyl-2-propanyl 2-(2-methoxy-2-oxoethyl)-1-piperazinecarboxylate;

Suppliers and Price of tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-BOC-2-METHOXYCARBONYLMETHYLPIPERAZINE 95.00%
5MG
$ 500.80

Alichem
tert-Butyl2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
5g
$ 1799.00

Alichem
tert-Butyl2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate
1g
$ 770.00

Total 10 raw suppliers

Chemical Property of tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

Chemical Property:

Vapor Pressure:0.000114mmHg at 25°C
Refractive Index:1.465
Boiling Point:336.2 °C at 760 mmHg
PKA:7.74±0.40(Predicted)
Flash Point:157.1 °C
PSA：67.87000
Density:1.084 g/cm³
LogP:1.02510

Purity/Quality:

99%, ^*data from raw suppliers

1-BOC-2-METHOXYCARBONYLMETHYLPIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate

There total 2 articles about tert-Butyl 2-(2-methoxy-2-oxoethyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: C₁₉H₂₈N₂O₄

: 183852-65-5
1-boc-2-methoxycarbonylmethylpiperazine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 141856-12-4
Methyl 4-Benzylpiperazin-2-ylacetate

: 183852-65-5
1-boc-2-methoxycarbonylmethylpiperazine

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / 4 h / 20 °C / Cooling with ice

2: hydrogen; palladium 10% on activated carbon / methanol / 20 °C

With palladium 10% on activated carbon; hydrogen; In methanol; dichloromethane;

Reference yield:

: 183852-65-5
1-boc-2-methoxycarbonylmethylpiperazine

: 7-bromo-2-(5-(3-chlorophenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)-1,5-naphthyridine

: 76-05-1
trifluoroacetic acid

: (x)C₂HF₃O₂*C₂₃H₂₁ClN₆O₂

Guidance literature:: 1-boc-2-methoxycarbonylmethylpiperazine; 7-bromo-2-(5-(3-chlorophenyl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)-1,5-naphthyridine; With (2-dicyclohexylphosphino-2’,6’-diisopropoxy-1,1‘-biphenyl)[2-(2’-methylamino-1,1’-biphenyl)]palladium(II) methanesulfonate; caesium carbonate; ruphos; In 1,4-dioxane; at 80 ℃; for 16h; Inert atmosphere;

With hydrogenchloride; In water; 1,2-dichloro-ethane; at 80 ℃; for 3h; Inert atmosphere;

trifluoroacetic acid; In water; acetonitrile; Inert atmosphere;