(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Base Information

Chemical Name:(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide
CAS No.:72737-95-2
Molecular Formula:C₁₆H₁₄N₄O₂
Molecular Weight:294.313
Hs Code.:

Synonyms:(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Suppliers and Price of (4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

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Chemical Property of (4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Chemical Property:

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Technology Process of (4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

There total 7 articles about (4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 72737-93-0
(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acid ethyl ester

: 72737-95-2
(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; Heating;

Reference yield:

: 28144-70-9,88-68-6
anthranilic acid amide

: 72737-95-2
(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: iodine / acetonitrile / 24 h / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 6 h / Reflux

3: hydrazine hydrate / ethanol / 1 h / 20 °C

With iodine; potassium carbonate; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bioorg.2019.103270

Reference yield:

: 100-52-7
benzaldehyde

: 72737-95-2
(4-oxo-2-phenyl-4H-quinazolin-3-yl)-acetic acidhydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: iodine / acetonitrile / 24 h / Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 6 h / Reflux

3: hydrazine hydrate / ethanol / 1 h / 20 °C

With iodine; potassium carbonate; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bioorg.2019.103270