Technology Process of (2S,3S,4S,5S)-4,5-bis(benzyloxy)-2-vinylhept-6-ene-1,3-diol
There total 8 articles about (2S,3S,4S,5S)-4,5-bis(benzyloxy)-2-vinylhept-6-ene-1,3-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium borohydride;
In
tetrahydrofuran; diethyl ether; water;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ja202610x
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: triethylamine; di-n-butylboron trifluoromethanesulphonate / dichloromethane / -78 - 0 °C / Inert atmosphere
1.2: 3 h / -78 - 15 °C / Inert atmosphere
2.1: lithium borohydride / tetrahydrofuran; diethyl ether; water / 0 - 20 °C / Inert atmosphere
With
lithium borohydride; triethylamine; di-n-butylboron trifluoromethanesulphonate;
In
tetrahydrofuran; diethyl ether; dichloromethane; water;
DOI:10.1021/ja202610x
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium hydride / N,N-dimethyl-formamide / 30 °C
2: toluene-4-sulfonic acid / methanol / 20 °C
3: iodine; 1H-imidazole; triphenylphosphine / tetrahydrofuran / Reflux
4: zinc / tetrahydrofuran; water / 40 °C / Sonication
5: triethylamine; di-n-butylboryl trifluoromethanesulfonate / dichloromethane / -78 °C
6: lithium borohydride / tetrahydrofuran; water / 0 - 20 °C
With
1H-imidazole; lithium borohydride; di-n-butylboryl trifluoromethanesulfonate; iodine; sodium hydride; toluene-4-sulfonic acid; triethylamine; triphenylphosphine; zinc;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1039/c5ob00532a
