(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Base Information

Chemical Name:(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one
CAS No.:1207454-88-3
Molecular Formula:C₁₆H₁₀F₃NO₂
Molecular Weight:305.256
Hs Code.:
Mol file:1207454-88-3.mol

Synonyms:(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Suppliers and Price of (E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of (E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Chemical Property:

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

There total 3 articles about (E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 59434-19-4
4-Amino-1(3H)-isobenzofuranon

: 1207454-88-3
(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Guidance literature:: With magnesium sulfate; In acetonitrile; at 20 ℃; Reflux;

Reference yield:

: 641-70-3
3-nitrophthalic acid anhydride

: 1207454-88-3
(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium tetrahydroborate / tetrahydrofuran / 3 h / 0 °C

1.2: pH 1

2.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 3 h / 25 °C / 760.05 Torr

3.1: magnesium sulfate / acetonitrile / 20 °C / Reflux

With sodium tetrahydroborate; hydrogen; magnesium sulfate; palladium 10% on activated carbon; In tetrahydrofuran; ethyl acetate; acetonitrile;

Reference yield:

: 65399-18-0
4-nitrophthalide

: 1207454-88-3
(E)-4-(4-(trifluoromethyl)benzylideneamino)isobenzofuran-1(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 3 h / 25 °C / 760.05 Torr

2: magnesium sulfate / acetonitrile / 20 °C / Reflux

With hydrogen; magnesium sulfate; palladium 10% on activated carbon; In ethyl acetate; acetonitrile;