2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Base Information

Chemical Name:2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one
CAS No.:884500-82-7
Molecular Formula:C₁₅H₁₁NO₃
Molecular Weight:253.257
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70470837
Wikidata:Q82299015
Mol file:884500-82-7.mol

Synonyms:884500-82-7;2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one;4H-Pyrano[2,3-b]pyridin-4-one, 2-(4-methoxyphenyl)-;2-(4-Methoxyphenyl)pyrano[2,3-b]pyridin-4-one;SCHEMBL311674;4H-Pyrano[2,3-b]pyridin-4-one,2-(4-methoxyphenyl)-;DTXSID70470837

Suppliers and Price of 2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)PYRANO[2,3-B]PYRIDIN-4-ONE 95.00%
1G
$ 952.01

Total 8 raw suppliers

Chemical Property of 2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:425.278°C at 760 mmHg
Flash Point:211.001°C
PSA：52.33000
Density:1.289g/cm³
LogP:2.86360
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:253.07389321
Heavy Atom Count:19
Complexity:372

Purity/Quality:

98% ^*data from raw suppliers

2-(4-METHOXYPHENYL)PYRANO[2,3-B]PYRIDIN-4-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)N=CC=C3

Technology Process of 2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one

There total 5 articles about 2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1301225-28-4
C₁₅H₁₂ClNO₃

: 884500-82-7
2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridine-4-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 6h; under air;
DOI:10.1002/anie.201007302

Reference yield: 64.0%

: 884501-75-1
1-(4-methoxyphenyl)-3-(2-methoxypyridin-3-yl)propane-1,3-dione

: 884500-82-7
2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridine-4-one

Guidance literature:: With PPA; at 90 ℃; for 1h;

Reference yield:

: 1452-94-4
ethyl 2-chloronicotinate

: 884500-82-7
2-(4-methoxyphenyl)-4H-pyrano[2,3-b]pyridine-4-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: 16 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 1.5 h / 0 - 20 °C / Reflux

2.2: 16 h / 0 - 20 °C

3.1: polyphosphoric acid / 1 h / 90 °C

With sodium hydride; In N,N-dimethyl-formamide;