Technology Process of 4-(4-fluorophenyl)-2-nitrodibenzofuran
There total 8 articles about 4-(4-fluorophenyl)-2-nitrodibenzofuran which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; potassium carbonate;
In
1,4-dioxane; water;
at 100 ℃;
for 20h;
Inert atmosphere;
DOI:10.1021/ol203442a
- Guidance literature:
-
With
copper diacetate; caesium carbonate; Trimethylacetic acid;
In
dimethyl sulfoxide;
at 140 ℃;
for 24h;
air;
DOI:10.1021/ol203442a
- Guidance literature:
-
Multi-step reaction with 4 steps
1: nitric acid; acetic acid / 15 - 20 °C
2: iodine / dimethyl sulfoxide / 110 °C
3: copper diacetate; caesium carbonate; Trimethylacetic acid / dimethyl sulfoxide / 24 h / 140 °C / air
4: bis-triphenylphosphine-palladium(II) chloride; potassium carbonate / 1,4-dioxane; water / 20 h / 100 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; iodine; nitric acid; copper diacetate; potassium carbonate; caesium carbonate; acetic acid; Trimethylacetic acid;
In
1,4-dioxane; water; dimethyl sulfoxide;
4: Suzuki coupling;
DOI:10.1021/ol203442a
