3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester

Base Information

Chemical Name:3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester
CAS No.:75806-14-3
Molecular Formula:C₁₀H₁₇NO₄Si
Molecular Weight:243.335
Hs Code.:2931900090
Mol file:75806-14-3.mol

Synonyms:3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester

Suppliers and Price of 3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
3-Butynoicacid,2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-,methylester
100mg
$ 114.00

American Custom Chemicals Corporation
2-[(METHOXYCARBONYL)AMINO]-4-(TRIMETHYLSILYL)-3-BUTYNOIC ACID METHYL ESTER 95.00%
5MG
$ 495.01

Total 11 raw suppliers

Chemical Property of 3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester

Chemical Property:

Vapor Pressure:0.00108mmHg at 25°C
Boiling Point:301°C at 760 mmHg
Flash Point:135.8°C
PSA：64.63000
Density:1.063g/cm³
LogP:1.15570

Purity/Quality:

99% ^*data from raw suppliers

3-Butynoicacid,2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-,methylester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester

There total 3 articles about 3-Butynoic acid, 2-[(methoxycarbonyl)amino]-4-(trimethylsilyl)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 64356-75-8
Chloro((methoxycarbonyl)amino)acetic acid methyl ester

: 14630-40-1
Bis(trimethylsilyl)ethyne

: 75806-14-3
methyl 1-<(trimethylsilyl)ethynyl>-N-carbomethoxyglycinate

Guidance literature:: With aluminum (III) chloride; In dichloromethane; at 20 ℃; Cooling with ice;

Reference yield:

: 64356-75-8
Chloro((methoxycarbonyl)amino)acetic acid methyl ester

: 75806-14-3
methyl 1-<(trimethylsilyl)ethynyl>-N-carbomethoxyglycinate

Guidance literature:

Reference yield:

: 143995-55-5
2--2-methoxyethanoate

: 75806-14-3
methyl 1-<(trimethylsilyl)ethynyl>-N-carbomethoxyglycinate

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus pentachloride / tetrachloromethane / 24 h / 20 °C

2: aluminum (III) chloride / dichloromethane / 20 °C / Inert atmosphere; Cooling with ice

With aluminum (III) chloride; phosphorus pentachloride; In tetrachloromethane; dichloromethane;
DOI:10.1016/j.tetlet.2016.10.106