Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-

Base Information

Chemical Name:Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-
CAS No.:310404-47-8
Molecular Formula:C17H13 N O5
Molecular Weight:311.29
Hs Code.:2925190090
Mol file:310404-47-8.mol

Synonyms:Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-;Benzenepropanoic acid,α-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-, (αR)-

Suppliers and Price of Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Benzenepropanoicacid,α-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(αR)-
250mg
$ 197.00

American Custom Chemicals Corporation
(ALPHA R)-ALPHA-[(1,3-DIHYDRO-1,3-DIOXO-2H-ISOINDOL-2-YL)OXY]-BENZENEPROPANOIC ACID 95.00%
5MG
$ 505.77

Total 13 raw suppliers

Chemical Property of Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-

Chemical Property:

PSA：83.91000
LogP:1.84800

Purity/Quality:

NLT 98% ^*data from raw suppliers

Benzenepropanoicacid,α-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(αR)- ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)-

There total 6 articles about Benzenepropanoic acid,-[(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)oxy]-,(aR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yloxy)-3-phenyl-propionic acid benzyl ester

: 310404-47-8
(R)-3-phenyl-2-phthalimidooxypropanoic acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; for 1h; under 760.051 Torr;
DOI:10.1021/jo0006573

Reference yield:

: 20312-36-1
L-3-phenyllactic acid

: 310404-47-8
(R)-3-phenyl-2-phthalimidooxypropanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: Cs₂CO₃ / methanol; H₂O / pH 7

1.2: 97 percent / dimethylformamide / 6 h / 20 °C

2.1: PPh₃; DIAD / CH₂Cl₂ / 0.67 h / -40 - -20 °C

3.1: H₂ / Pd/C / methanol / 1 h / 760.05 Torr

With di-isopropyl azodicarboxylate; hydrogen; caesium carbonate; triphenylphosphine; palladium on activated charcoal; In methanol; dichloromethane; water; 1.1: deprotonation / 1.2: benzylation / 2.1: Substitution / 3.1: Hydrogenolysis;
DOI:10.1021/jo0006573