4-Imidazo[1,2-a]pyridin-2-ylbenzamide

Base Information

Chemical Name:4-Imidazo[1,2-a]pyridin-2-ylbenzamide
CAS No.:118000-49-0
Molecular Formula:C₁₄H₁₁N₃O
Molecular Weight:237.261
Hs Code.:
DSSTox Substance ID:DTXSID501287323
Mol file:118000-49-0.mol

Synonyms:4-imidazo[1,2-a]pyridin-2-ylbenzamide;118000-49-0;SCHEMBL3663283;DTXSID501287323;benzamide,4-imidazo[1,2-a]pyridin-2-yl-;AQ-776/42801579

Suppliers and Price of 4-Imidazo[1,2-a]pyridin-2-ylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-IMIDAZO[1,2-A]PYRIDIN-2-YL-BENZAMIDE 95.00%
5MG
$ 497.04

Total 0 raw suppliers

Chemical Property of 4-Imidazo[1,2-a]pyridin-2-ylbenzamide

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:237.090211983
Heavy Atom Count:18
Complexity:312

Purity/Quality:: 4-IMIDAZO[1,2-A]PYRIDIN-2-YL-BENZAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC2=NC(=CN2C=C1)C3=CC=C(C=C3)C(=O)N

Technology Process of 4-Imidazo[1,2-a]pyridin-2-ylbenzamide

There total 5 articles about 4-Imidazo[1,2-a]pyridin-2-ylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 55843-91-9
4-(H-imidazo[1,2-a]pyridin-2-yl)benzonitrile

: 118000-49-0
2-(4-Aminocarbonyl-phenyl)-imidazo[1,2-a]pyridine

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In methanol; at 50 ℃; for 1h;
DOI:10.1002/jhet.5570250119

Reference yield:

: 504-29-0
2-aminopyridine

: 118000-49-0
2-(4-Aminocarbonyl-phenyl)-imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 2)HBr / 1) acetone, reflux, 3 h, 2) methanol, reflux, 60 min

2: 56 percent / dimethylformamide / 24 h / Heating

3: 80 percent / 6N aq. NaOH, 30percent H₂O₂ / methanol / 1 h / 50 °C

With sodium hydroxide; hydrogen bromide; dihydrogen peroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570250119

Reference yield:

: 34658-66-7
2-(4-bromophenyl)imidazo[1,2-a]pyridine

: 118000-49-0
2-(4-Aminocarbonyl-phenyl)-imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 56 percent / dimethylformamide / 24 h / Heating

2: 80 percent / 6N aq. NaOH, 30percent H₂O₂ / methanol / 1 h / 50 °C

With sodium hydroxide; dihydrogen peroxide; In methanol; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570250119