34658-66-7

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-Bromophenyl)imidazo[1,2-a]pyridine is used as an intermediate for the development of new pharmaceutical compounds. Its unique chemical structure allows it to be a key component in the creation of drugs targeting specific medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(4-Bromophenyl)imidazo[1,2-a]pyridine is utilized as a raw material for the production of various agrochemicals. Its properties contribute to the effectiveness of these products in agricultural applications, such as pest control and crop protection.
Used in Dye Industry:
2-(4-Bromophenyl)imidazo[1,2-a]pyridine is also employed as a crucial raw material in the dye industry. Its chemical composition plays a vital role in the synthesis of dyes with specific color properties and characteristics, catering to various industrial needs.

InChI:InChI=1/C13H9BrN2/c14-11-6-4-10(5-7-11)12-9-16-8-2-1-3-13(16)15-12/h1-9H

Upstream product

• 131947-28-9 2-(4-Bromophenyl)-3-chloroimidazo<1,2-a>pyrimidine 
• 504-29-0 2-aminopyridine 
• 98475-05-9 α-tosyloxy-4-bromoacetophenone 
• 99-90-1 para-bromoacetophenone 
• 766-96-1 4-bromo-1-ethynylbenzene 
• 110-86-1 pyridine 
• 299456-72-7 1-(4-bromophenyl)ethanone O-acetyl oxime 
• 57342-22-0 2-bromo-1-(4-bromophenyl)ethanone oxime 
• 99-73-0 para-bromophenacyl bromide 
• 70-11-1 α-bromoacetophenone 
• 59862-55-4 p-bromoacetophenone oxime 
• 1585-07-5 1-bromo-4-ethylbenzene 
• 4209-02-3 1-(4-bromophenyl)-2-chloroethan-1-one 
• 75-52-5 nitromethane 

Downstream Products

• 76458-77-0 [2-(4-Bromo-phenyl)-imidazo[1,2-a]pyridin-3-yl]-phenyl-diazene 
• 55843-91-9 4-(H-imidazo[1,2-a]pyridin-2-yl)benzonitrile 
• 131947-28-9 2-(4-Bromophenyl)-3-chloroimidazo<1,2-a>pyrimidine 
• 205655-27-2 2-(4'-bromophenyl)-3-nitrosoimidazo[1,2-a]pyridine 
• 349482-10-6 1-[2-(4-bromo-phenyl)-imidazo[1,2-a]pyridin-3-yl]-2-chloro-2,2-difluoro-ethanone 
• 131947-31-4 2-(4-bromophenyl)-3-(4-tolylthio)imidazo<1,2-a>pyridine 
• 138023-18-4 2-(4-Bromophenyl)-3-bromoimidazo<1,2-a>pyridine 
• 1246635-31-3 N-[4-(imidazo[1,2-a]pyridin-2-yl)phenyl]-N,N',N'-triphenyl-1,4-phenylenediamine 
• 1246635-30-2 N-[4-(imidazo[1,2-a]pyridin-2-yl)phenyl]-N,9-diphenyl-9H-carbazole-3-amine 
• 1246635-29-9 4-(imidazo[1,2-a]pyridine-2-yl)-4'-(9H-carbazol-9-yl)triphenylamine 

Relevant academic research and scientific papers

Reducing Defects Density and Enhancing Hole Extraction for Efficient Perovskite Solar Cells Enabled by π-Pb2+ Interactions

Molecular doping is an of significance approach to reduce defects density of perovskite and to improve interfacial charge extraction in perovskite solar cells. Here, we show a new strategy for chemical doping of perovskite via an organic small molecule, w

Oxidation Potential-Guided Electrochemical Radical-Radical Cross-Coupling Approaches to 3-Sulfonylated Imidazopyridines and Indolizines

Oxidation potential-guided electrochemical radical-radical cross-coupling reactions between N-heteroarenes and sodium sulfinates have been established. Thus, simple cyclic voltammetry measurement of substrates predicts the likelihood of successful radical-radical coupling reactions, allowing the simple and direct synthetic access to 3-sulfonylated imidazopyridines and indolizines. The developed electrochemical radical-radical cross-coupling reactions to sulfonylated N-heteroarenes boast the green synthetic nature of the reactions that are oxidant- and metal-free.

Solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines by grindstone chemistry

The present work describes the solvent and catalyst-free synthesis of imidazo[1,2-a]pyridines in excellent to nearly quantitative yields from 2-aminopyridines and a wide variety of ω-bromomethylketones using a grindstone procedure at 25°C to 30°C for 3 to

Molecular iodine enabled generation of iminyl radicals from oximes: A facile route to imidazo[1,2-a]pyridines and its regioselective C-3 sulfenylated products from simple pyridines

An iodine promoted simple and environment friendly protocol has been developed to access imidazo[1,2-a]pyridines from unfunctionalized pyridines and oxime esters. This straightforward method efficiently converts the substrates into corresponding products affording moderate to good yields with large functional group tolerance. Additionally extensive investigation revealed that regioselective domino C-3 methyl sulfenylated imidazo[1,2-a]pyridines were also accessible first time from pyridines and oxime esters in DMSO solvent. The reaction operates through metal-free generation of iminyl radicals from easily accessible oxime esters, to build up the second heterocyclic ring on pyridines.

Synthetic method of imidazopyridine compounds

The invention provides a novel method for synthesizing imidazopyridine compounds. According to the invention, aminopyridine compounds and sulfur ylide are used as original reaction substrates, iron phthalocyanine (FeIIPc) is used as a catalyst, and a series of the imidazopyridine compounds are obtained under the condition that the advantages of mildness, greenness, high efficiency, wide substrateuniversality and the like are achieved.

SUBSTITUTED DIAZAHETERO-BICYCLIC COMPOUNDS AND THEIR USE

The present application relates to novel (imidazo[1,2-a]pyridin-3-yl)methyl-substituted diazaheterobicyclic compounds, to processes for preparation thereof, to the use thereof alone or in combinations for treatment and/or prevention of diseases, and to th

Micellar Catalysis: Visible-Light Mediated Imidazo[1,2-a]pyridine C—H Amination with N-Aminopyridinium Salt Accelerated by Surfactant in Water

A light-promoted metal-free protocol for the amination of imidazo[1,2-a]pyridines with N-aminopyridinium salt by the assistance of surfactants in water was reported, charactering mild and environmentally benign conditions, as well as great functional grou

A simple and efficient route to 2-arylimidazo[1,2-a]pyridines and zolimidine using automated grindstone chemistry

A green and efficient mechanochemical method for the synthesis of a series of 2-arylimidazo[1,2-a]pyridines was developed using an electrical grinder. I2 catalyzed mechanochemical grinding facilitates the cyclocondensation reaction between various aryl methyl ketones and 2-aminopyridines to afford 2-arylimidazo[1,2-a]pyridines in good yields at ambient temperature. The method was successfully used for the gram-scale synthesis of a marketed drug, zolimidine. The noticeable advantages of this environmentally sustainable protocol include mild conditions, simple instrumentation, inexpensive catalyst, atom economy, short reaction time etc.

Microwave-assisted synthesis and luminescent activity of imidazo[1,2-a]pyridine derivatives

In this work, a series of phenacyl bromide derivatives was synthesized and employed as key intermediate for the synthesis of substituted imidazo[1,2-a]pyridines. First, phenacyl bromide molecules were obtained from the bromination reaction of acetophenones assisted by microwave irradiation, obtaining the products 4a-v in a 15 minutes reaction with yields in the range of 50% to 99%. Subsequently, the conjugation of these molecules with 2-aminopyridine conduced to the production of imidazo[1,2-a]pyridine derivatives (7a-v) in a 60-second reaction with yields of 24% to 99%. Improved yields were determined with respect to those obtained with more tedious methodologies like thermally and mechanically assisted routes. Intense luminescence emissions in the purple and blue regions of the electromagnetic spectra were observed under UV excitation according to the nature of the substituents. This environmentally friendly methodology is expected to constitute an important class of organic compounds for the development of biomarkers, photochemical sensors, and medicinal applications.

PhI(OAc)2-mediated oxidative C[sbnd]H sulfoximination of imidazopyridines under mild conditions

A facile protocol for direct oxidative C[sbnd]N bond coupling of unactivated imidazo[1,2-a]pyridines with NH-sulfoximines was disclosed using sulfoximines as the nitrogen sources in the presence of (diacetoxy)iodobenzene (PhI(OAc)2). The reacti