(R)-m-Methyl-a-phenethylamin

Base Information

• Chemical Name: (R)-m-Methyl-a-phenethylamin
• CAS No.: 138457-19-9
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.209
• Hs Code.: 2921499090
• Mol file: 138457-19-9.mol

Synonyms:Benzenemethanamine,a,3-dimethyl-, (R)-; (R)-m-Methyl-a-phenethylamine; (R)-m-Methyl-a-phenylethylamine

Chemical Property of (R)-m-Methyl-a-phenethylamin

Chemical Property:

• Boiling Point: 205.6±9.0 °C(Predicted)
• PKA: 9.08±0.10(Predicted)
• PSA: 26.02000
• Density: 0.945±0.06 g/cm3(Predicted)
• LogP: 2.71500
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

(R)-1-m-Tolylethanamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-m-Methyl-a-phenethylamin

There total 32 articles about (R)-m-Methyl-a-phenethylamin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-Methylacetophenone (585-74-0) → 1-(m-tolyl)ethan-1-amine (138457-19-9)

Guidance literature:

3-Methylacetophenone; With Ru⁽²⁺⁾*2C₂H₃O₂^(1-)*C₇₇H₁₀₈O₆P₂; ammonium acetate; hydrogen; In 2,2,2-trifluoroethanol; at 20 ℃; for 20h; under 7600.51 - 38002.6 Torr; Heating; Autoclave;

With hydrogenchloride; In 2,2,2-trifluoroethanol; water; at 80 ℃; for 6h;

Reference yield: 87.0%

3-Methylacetophenone (585-74-0) → (1R)-1-(3-methylphenyl)ethan-1-amine (138457-19-9)

Guidance literature:

With Ru⁽²⁺⁾*2C₂H₃O₂^(1-)*C₇₇H₁₀₈O₆P₂; hydrogen; sodium acetate; In 2,2,2-trifluoroethanol; at 100 ℃; for 24h; under 42754.3 Torr; enantioselective reaction; Autoclave;

DOI:10.1021/jacs.7b12898

Reference yield: 81.0%

3-Methylacetophenone (585-74-0) → 1-(m-tolyl)ethylamine (70138-19-1,138457-19-9)

Guidance literature:

With N,N'-bis(salicylidene)-1,2-phenylene-diaminocobalt(II); ammonia; hydrogen; In water; at 130 ℃; for 24h; Autoclave;

DOI:10.1039/c9sc04963k

upstream raw materials:

formamide

3-Methylacetophenone

ammonium formate

1-m-tolyl-ethanone oxime

Downstream raw materials:

1-(m-Methylphenyl)-1-formylaminethan

4-(4-((1-(m-tolyl)ethyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenol hydrobromide

3-Methylacetophenone

(R)-2-methoxy-N-(1-m-tolylethyl)acetamide