(2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid

Base Information

Chemical Name:(2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid
CAS No.:109299-79-8
Molecular Formula:C12H21BN2O4
Molecular Weight:268.121
Hs Code.:2933599090
DSSTox Substance ID:DTXSID90371039
Wikidata:Q72469973
Mol file:109299-79-8.mol

Synonyms:109299-79-8;2,4-Di(tert-butoxy)pyrimidine-5-boronic acid;(2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid;2,4-ditert-butoxypyrimidin-5-ylboronic acid;2,4-Di-tert-butoxypyrimidine-5-boronic acid;[2,4-bis[(2-methylpropan-2-yl)oxy]pyrimidin-5-yl]boronic acid;MFCD01318980;2,4-di-tert-butoxypyrimidin-5-ylboronic acid;C12H21BN2O4;(2,4-Di-tert-butoxypyrimidin-5-yl)boronicacid;AF-399/25030004;SCHEMBL561353;DTXSID90371039;SOJAZSRAXNFWRH-UHFFFAOYSA-N;AMY13316;AKOS000320209;AB08792;SB60713;2,4-Ditertbutoxypyrimidin-5-ylboronicacid;BS-22459;SY300425;2,4-Ditert-butoxypyrimidin-5-ylboronicacid;FT-0605405;FT-0609958;2,4-Di-tert-butoxy-pyrimidine-5-boronic acid;A22930;D71289;Dihydroxy(2,4-di-tert-butoxypyrimidine-5-yl)borane;J-018067;2,4-ditert-butoxypyrimidin-5-ylboronic acid, AldrichCPR

Suppliers and Price of (2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Di(tert-butoxy)pyrimidine-5-boronicAcid
250mg
$ 55.00

TRC
2,4-Di(tert-butoxy)pyrimidine-5-boronicAcid
1g
$ 120.00

Matrix Scientific
2,6-Di-tert-butoxypyrimidine-5-boronic acid hydrate 97%
1g
$ 671.00

Crysdot
(2,4-Di-tert-butoxypyrimidin-5-yl)boronicacid 95+%
5g
$ 353.00

Crysdot
(2,4-Di-tert-butoxypyrimidin-5-yl)boronicacid 95+%
1g
$ 94.00

AOBChem
2,4-Di(tert-butoxy)pyrimidine-5-boronicacid 97%
25g
$ 770.00

AOBChem
2,4-Di(tert-butoxy)pyrimidine-5-boronic acid 97%
50g
$ 1332.00

AOBChem
2,4-Di(tert-butoxy)pyrimidine-5-boronicacid 97%
100g
$ 2130.00

AOBChem
2,4-Di(tert-butoxy)pyrimidine-5-boronicacid 97%
5g
$ 230.00

AOBChem
2,4-Di(tert-butoxy)pyrimidine-5-boronicacid 97%
1g
$ 64.00

Total 26 raw suppliers

Chemical Property of (2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid

Chemical Property:

Vapor Pressure:3.29E-08mmHg at 25°C
Refractive Index:1.498
Boiling Point:431.408 °C at 760 mmHg
Flash Point:214.708 °C
PSA：93.93000
Density:1.134 g/cm³
LogP:0.44670
Storage Temp.:2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:268.1594373
Heavy Atom Count:19
Complexity:288

Purity/Quality:

97% ^*data from raw suppliers

2,4-Di(tert-butoxy)pyrimidine-5-boronicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CN=C(N=C1OC(C)(C)C)OC(C)(C)C)(O)O
Uses 2,4-Di(tert-butoxy)pyrimidine-5-boronic Acid is a useful reagent for the synthesis of flexible nucleosides, which could create potential anticancer and antiviral drugs.

Technology Process of (2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid

There total 1 articles about (2,4-Di-tert-butoxypyrimidin-5-yl)boronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19752-61-5
5-bromo-2,4-di(tert-butoxy)pyrimidine

: 109299-79-8
(2,4-di-tert-butoxypyrimidin-5-yl)boronic acid

Guidance literature:: With n-butyllithium; triethyl borate; In tetrahydrofuran; at -100 ℃;
DOI:10.1016/j.jfluchem.2011.11.005

Reference yield: 89.0%

: 108-36-1
1,3-dibromobenzene

: 109299-79-8
(2,4-di-tert-butoxypyrimidin-5-yl)boronic acid

: 5-(3'-bromophenyl)-2,4-di-t-butoxypyrimidine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,2-dimethoxyethane; for 1h; Heating;
DOI:10.1002/jhet.5570320410

Reference yield: 74.0%

: (6aS,7S,10aS)-4-chloro-10a-(4-fluorophenyl)-2,7-dimethyl-5,6a,7,9,10,10a-hexahydrobenzo[h]quinazolin-8(6H)-one

: 109299-79-8
(2,4-di-tert-butoxypyrimidin-5-yl)boronic acid

: 5-[(6aS,7S,10aS)-10a-(4-fluorophenyl)-2,7-dimethyl-8-oxo-5,6,6a,7,8,9,10,10a-octahydrobenzo[h]quinazolin-4-yl]pyrimidine-2,4(1H,3H)-dione

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 80 ℃; for 22h; Inert atmosphere; Sealed tube;