Multi-step reaction with 10 steps
1: 76 percent / I2, NaHCO3 / H2O / 3 h / 60 °C
2: 88 percent / pyridine / CHCl3 / 1.) room temp., 0.5 h, 2.) 50-60 deg C, 2 h
3: 64 percent / hexamethylphosphoric acid triamide / 3 h / 150 °C
4: 95 percent / SnCl2, HCl / diethyl ether; CH2Cl2 / 2 h
5: 1.) Mg / 1.) diethyl ether, 30 min, 2.) THF, diethyl ether, overnight, reflux
6: CrO3, conc. H2SO4 / acetone; H2O
7: 85 percent / conc. HCl / H2O / 1 h / Heating
8: Cl2 / acetic acid / 0.03 h / Ambient temperature
9: Br2 / acetic acid / Irradiation
10: propan-2-ol
With
pyridine; chromium(VI) oxide; hydrogenchloride; sulfuric acid; bromine; iodine; chlorine; sodium hydrogencarbonate; magnesium; tin(ll) chloride;
In
N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; dichloromethane; chloroform; water; acetic acid; isopropyl alcohol; acetone;