2-BROMO-5-FLUORO-3-NITROPYRIDINE

Base Information

Chemical Name:2-BROMO-5-FLUORO-3-NITROPYRIDINE
CAS No.:652160-72-0
Molecular Formula:C5H2BrFN2O2
Molecular Weight:220.985
Hs Code.:2933399090
Mol file:652160-72-0.mol

Synonyms:2-Bromo-5-fluoro-3-nitropyridine;

Suppliers and Price of 2-BROMO-5-FLUORO-3-NITROPYRIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-5-fluoro-3-nitropyridine
500mg
$ 65.00

TRC
2-Bromo-5-fluoro-3-nitropyridine
100mg
$ 45.00

Oakwood
2-Bromo-5-fluoro-3-nitropyridine 98%
10g
$ 175.00

Matrix Scientific
2-Bromo-5-fluoro-3-nitropyridine 95+%
1g
$ 29.00

Matrix Scientific
2-Bromo-5-fluoro-3-nitropyridine 95+%
5g
$ 98.00

Matrix Scientific
2-Bromo-5-fluoro-3-nitropyridine 95+%
25g
$ 365.00

Labseeker
2-BROMO-5-FLUORO-3-NITROPYRIDINE 95
25g
$ 585.00

Crysdot
2-Bromo-5-fluoro-3-nitropyridine 98%
25g
$ 297.00

Crysdot
2-Bromo-5-fluoro-3-nitropyridine 98%
100g
$ 970.00

ChemScene
2-Bromo-5-fluoro-3-nitropyridine ≥97.0%
10g
$ 155.00

Total 49 raw suppliers

Chemical Property of 2-BROMO-5-FLUORO-3-NITROPYRIDINE

Chemical Property:

Appearance/Colour:Yellow liquid
Vapor Pressure:0.118mmHg at 25°C
Refractive Index:1.586
Boiling Point:227.3 °C at 760 mmHg
PKA:-5.67±0.20(Predicted)
Flash Point:91.2 °C
PSA：58.71000
Density:1.923 g/cm³
LogP:2.41460
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Water Solubility.:Slightly soluble in water.

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-5-fluoro-3-nitropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-BROMO-5-FLUORO-3-NITROPYRIDINE

There total 5 articles about 2-BROMO-5-FLUORO-3-NITROPYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 136888-20-5
5-fluoro-2-hydroxy-3-nitropyridine

: 652160-72-0
2-bromo-5-fluoro-3-nitropyridine

Guidance literature:: With N,N-dimethyl-formamide; phosphorus(V) oxybromide; at 20 - 110 ℃; for 3.08333h;

Reference yield:

: 6628-77-9
6-methoxy-pyridin-3-ylamine

: 652160-72-0
2-bromo-5-fluoro-3-nitropyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrafluoroboric acid; sodium nitrite / ethanol; water / 3 h / 0 °C / Inert atmosphere

1.2: 4 h / 100 °C / Inert atmosphere

2.1: hydrogenchloride / toluene / 2 h / Inert atmosphere; Sealed tube; Heating

3.1: sulfuric acid; nitric acid / 1 h / 20 - 80 °C / Inert atmosphere

4.1: phosphorus(V) oxybromide / N,N-dimethyl-formamide / 3.08 h / 20 - 110 °C / Inert atmosphere

With hydrogenchloride; tetrafluoroboric acid; sulfuric acid; nitric acid; sodium nitrite; phosphorus(V) oxybromide; In ethanol; water; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm3016377

Reference yield:

: 51173-04-7
5-fluoro-2-methoxypyridine

: 652160-72-0
2-bromo-5-fluoro-3-nitropyridine

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride / toluene / 2 h / Inert atmosphere; Sealed tube; Heating

2: sulfuric acid; nitric acid / 1 h / 20 - 80 °C / Inert atmosphere

3: phosphorus(V) oxybromide / N,N-dimethyl-formamide / 3.08 h / 20 - 110 °C / Inert atmosphere

With hydrogenchloride; sulfuric acid; nitric acid; phosphorus(V) oxybromide; In N,N-dimethyl-formamide; toluene;
DOI:10.1021/jm3016377