Desonide delta 9 (11) analog

Base Information

Chemical Name:Desonide delta 9 (11) analog
CAS No.:5541-37-7
Molecular Formula:C₂₄H₃₀O₅
Molecular Weight:398.499
Hs Code.:
Mol file:5541-37-7.mol

Synonyms:(4aS,6aS,6bS,9aR)-6b-(2-Hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,6,6a,6b,9a,10,10a,10b,11,12-decahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

Suppliers and Price of Desonide delta 9 (11) analog

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
9-Desfluoro-11-dehydroxy-9(11)-eneTriamcinoloneAcetonide
25mg
$ 215.00

Total 9 raw suppliers

Chemical Property of Desonide delta 9 (11) analog

Chemical Property:

Melting Point:>200°C (dec.)
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

95%+HPLC ^*data from raw suppliers

9-Desfluoro-11-dehydroxy-9(11)-eneTriamcinoloneAcetonide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 9-Desfluoro-11-dehydroxy-9(11)-ene Triamcinolone Acetonide is an impurity of Triamcinolone Acetonide (T767165) which is an antiasthmatic (inhalant) and antiallergic (nasal).

Technology Process of Desonide delta 9 (11) analog

There total 3 articles about Desonide delta 9 (11) analog which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 39672-76-9
(10S,13S,16R,17S)-16,17-Dihydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-6,7,8,10,12,13,14,15,16,17-decahydro-cyclopenta[a]phenanthren-3-one

: 67-64-1
acetone

: 5541-37-7
(4aS,6aS,6bS,9aR)-6b-(2-Hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,6,6a,6b,9a,10,10a,10b,11,12-decahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

Guidance literature:: With perchloric acid; at -5 - 5 ℃; Cooling with ice;

Reference yield:

: C₂₄H₃₂O₄

: 5541-37-7
(4aS,6aS,6bS,9aR)-6b-(2-Hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,6,6a,6b,9a,10,10a,10b,11,12-decahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: formic acid; potassium permanganate / acetone / -5 - 5 °C

2: toluene-4-sulfonic acid / dichloromethane / 20 °C

3: perchloric acid / -5 - 5 °C / Cooling with ice

With potassium permanganate; formic acid; perchloric acid; toluene-4-sulfonic acid; In dichloromethane; acetone;

Reference yield:

: C₂₄H₃₄O₆

: 5541-37-7
(4aS,6aS,6bS,9aR)-6b-(2-Hydroxy-acetyl)-4a,6a,8,8-tetramethyl-4a,6,6a,6b,9a,10,10a,10b,11,12-decahydro-7,9-dioxa-pentaleno[2,1-a]phenanthren-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / dichloromethane / 20 °C

2: perchloric acid / -5 - 5 °C / Cooling with ice

With perchloric acid; toluene-4-sulfonic acid; In dichloromethane;