1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt

Base Information

• Chemical Name: 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt
• CAS No.: 39906-59-7
• Molecular Formula: C₁₆H₁₇N₂O₅S*K
• Molecular Weight: 388.486
• Mol file: 39906-59-7.mol

Synonyms:1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt

Chemical Property of 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt

There total 1 articles about 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid; potassium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

Penicillin G potassium (113-98-4) → 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid; potassium salt (39906-59-7)

Guidance literature:

With (NH₄)6Mo₇O₄₀; dihydrogen peroxide; In water; at 20 ℃; for 0.75h; Product distribution; various catalysts and temperatures, different substrates;

Reference yield:

1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid; potassium salt (39906-59-7) → Penicillin G 1-(s)-oxide (4052-54-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) KI, (ii) H₂O₂, AcOH

2: H₂ / Pd-C / H₂O

With hydrogen; palladium on activated charcoal; In water;

DOI:10.1016/S0040-4039(00)70886-0

Reference yield:

chloroacetonitrile (107-14-2) + 1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ4-penicillanic acid; potassium salt (39906-59-7) → 1,1-dioxo-6β-(2-phenyl-acetylamino)-1λ6-penicillanic acid cyanomethyl ester (99673-34-4)

Guidance literature:

Multistep reaction; (i) KI, (ii) KMnO₄, AcOH;

DOI:10.1016/S0040-4039(00)70886-0

upstream raw materials:

Penicillin G potassium

Downstream raw materials:

1ξ-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid cyanomethyl ester

1,1-dioxo-6β-(2-phenyl-acetylamino)-1λ⁶-penicillanic acid cyanomethyl ester

Penicillin G 1-(s)-oxide