(E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride

Base Information

• Chemical Name: (E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride
• CAS No.: 1280634-82-3
• Molecular Formula: C₁₉H₁₈F₄N₂O*ClH
• Molecular Weight: 402.819
• Mol file: 1280634-82-3.mol

Synonyms:(E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride

Chemical Property of (E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of (E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride

There total 1 articles about (E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-1-benzyl-4-(4-fluorophenyl)piperidin-3-one O-4-trifluoromethylbenzyl oxime (1280635-08-6) → (E)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride (1280634-82-3) + (Z)-4-(4-fluorophenyl)piperidin-3-one O-4-(trifluoromethyl)benzyl oxime hydrochloride (1280634-83-4)

Guidance literature:

With hydrogenchloride; 10% palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 30h; under 760.051 Torr; pH=3; optical yield given as %de;

DOI:10.1016/j.ejmech.2010.12.018

upstream raw materials:

(Z)-1-benzyl-4-(4-fluorophenyl)piperidin-3-one O-4-trifluoromethylbenzyl oxime