3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine

Base Information

• Chemical Name: 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine
• CAS No.: 862507-90-2
• Molecular Formula: C₁₉H₁₉FN₄
• Molecular Weight: 322.385

Synonyms:3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine

Chemical Property of 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine

There total 1 articles about 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

1-ethynyl-4-fluorobenzene (766-98-3) + 5-bromo-3-(2,2-dimethyl-propyl)-3H-imidazo[4,5-b]pyridin-2-yl-amine hydrobromide (862507-89-9) → 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine (862507-90-2)

Guidance literature:

With copper(l) iodide; triethylamine; palladium diacetate; triphenylphosphine; In ethanol; toluene; for 5.25h;

Reference yield: 88.0%

3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine (862507-90-2) → 1-[2-amino-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-5-yl]-2-(4-fluorophenyl)ethane-1,2-dione (862507-91-3)

Guidance literature:

With potassium permanganate; water; sodium hydrogencarbonate; magnesium sulfate; at 40 - 45 ℃; for 3h;

Reference yield: 84.0%

3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine (862507-90-2) + methanesulfonic acid (75-75-2,98527-29-8) → 2-amino-3-(2,2-dimethyl-propyl)-5-[2-(4-fluorophenyl)-2-oxo-acetyl]-3H-imidazo[4,5-b]pyridin-1-ium methanesulfonate (862507-92-4)

Guidance literature:

With formic acid; hydrogen bromide; dimethyl sulfoxide; at 105 - 107 ℃;

upstream raw materials:

1-ethynyl-4-fluorobenzene

5-bromo-3-(2,2-dimethyl-propyl)-3H-imidazo[4,5-b]pyridin-2-yl-amine hydrobromide

Downstream raw materials:

2-amino-3-(2,2-dimethyl-propyl)-5-[2-(4-fluorophenyl)-2-oxo-acetyl]-3H-imidazo[4,5-b]pyridin-1-ium methanesulfonate

1-[2-amino-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-5-yl]-2-(4-fluorophenyl)ethane-1,2-dione

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 862507-90-2 3-(2,2-dimethyl-propyl)-5-(4-fluoro-phenylethynyl)-3H-imidazo[4,5-b]pyridin-2-ylamine

Send

Send

Metric Ton KG G Pound L ML

Send

Send