ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER

Base Information

• Chemical Name: ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER
• CAS No.: 118286-19-4
• Molecular Formula: C17H18O3S
• Molecular Weight: 302.394
• Hs Code.: 2930909090
• Mol file: 118286-19-4.mol

Synonyms:Aceticacid, [(diphenylmethyl)sulfinyl]-, ethyl ester (9CI);

Chemical Property of ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER

Chemical Property:

• Appearance/Colour: White Solid
• Refractive Index: 1.597
• Boiling Point: 492.7 °C at 760 mmHg
• Flash Point: 251.8 °C
• PSA: 62.58000
• Density: 1.216 g/cm³
• LogP: 3.95350
• Solubility.: Chloroform, Dichloromethane, Ethyl Acetate, Methanol

Purity/Quality:

98%Min ^*data from raw suppliers

[(Diphenylmethyl)sulfinyl]aceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: [(Diphenylmethyl)sulfinyl]acetic Acid Ethyl Ester (cas# 118286-19-4) is a compound useful in organic synthesis.

Technology Process of ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER

There total 5 articles about ACETIC ACID, [(DIPHENYLMETHYL)SULFINYL]-, ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(diphenylmethyl)(ethyl acetate)sulfide (63547-23-9) → (diphenylmethyl)(ethyl acetate)sulfoxide (118286-19-4)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; for 4h; Inert atmosphere;

Reference yield:

(benzhydrylthio)acetic acid (63547-22-8) → (diphenylmethyl)(ethyl acetate)sulfoxide (118286-19-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 99 percent / H₂SO₄ / Heating

2: H₂SO₄; 2-propanol; aq. H₂O₂ / methanol / 20 °C

With sulfuric acid; dihydrogen peroxide; isopropyl alcohol; In methanol;

DOI:10.1016/j.tetasy.2004.01.039

Reference yield:

1,1-Diphenylmethanol (91-01-0) → (diphenylmethyl)(ethyl acetate)sulfoxide (118286-19-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / trifluoroacetic acid / 3 h / 20 °C

2: 99 percent / H₂SO₄ / Heating

3: H₂SO₄; 2-propanol; aq. H₂O₂ / methanol / 20 °C

With sulfuric acid; dihydrogen peroxide; isopropyl alcohol; trifluoroacetic acid; In methanol;

DOI:10.1016/j.tetasy.2004.01.039

upstream raw materials:

(diphenylmethyl)(ethyl acetate)sulfide

1,1-Diphenylmethanol

(benzhydrylthio)acetic acid

Diphenylmethane

Downstream raw materials:

modafinil acid

Nuvigil

(R)-Modafinil acid

(S)-(+)-(diphenylmethanesulfinyl)acetic acid

Refernces

• 1、 Jung, Jae-Chul,Lee, Yeonju,Son, Jee-Young,Lim, Eunyoung,Jung, Mankil,Oh, Seikwan. "Simple synthesis of modafinil derivatives and their anti-inflammatory activity". . p. 10446 - 10458. Retrieved 2012/11/07.