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1-(3-Hydroxyphenyl)piperazine

Base Information
  • Chemical Name:1-(3-Hydroxyphenyl)piperazine
  • CAS No.:59817-32-2
  • Molecular Formula:C10H14 N2 O
  • Molecular Weight:178.234
  • Hs Code.:2933599090
  • European Community (EC) Number:626-688-8
  • DSSTox Substance ID:DTXSID00371469
  • Wikidata:Q72481111
  • Mol file:59817-32-2.mol
1-(3-Hydroxyphenyl)piperazine

Synonyms:59817-32-2;1-(3-Hydroxyphenyl)piperazine;3-(piperazin-1-yl)phenol;3-piperazin-1-ylphenol;1-(3-Hydroxyphenyl) piperazine;3-(1-Piperazino)phenol;n-(3-hydroxyphenyl)piperazine;Phenol, 3-(1-piperazinyl)-;3-(1-piperazinyl)phenol;1-(3-HYDROXYPHENYL)-PIPERAZINE;3-hydroxyphenylpiperazine;3-piperazin-1-yl-phenol;3-hydroxyphenyl piperazine;3-piperazine-1-yl-phenol;Oprea1_613831;SCHEMBL788160;DTXSID00371469;AYGYICRITMSJOC-UHFFFAOYSA-N;BBL028052;MFCD00052896;STL373272;AKOS001393913;FS-1233;1-(3-Hydroxyphenyl) piperazine, 97%;CS-0106190;FT-0629178;EN300-21779;A832481;Z118507070

Suppliers and Price of 1-(3-Hydroxyphenyl)piperazine
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 1-(3-Hydroxyphenyl) piperazine
  • 2.5g
  • $ 45.00
  • SynQuest Laboratories
  • 3-(Piperazin-1-yl)phenol 97%
  • 250 mg
  • $ 29.00
  • Sigma-Aldrich
  • 1-(3-Hydroxyphenyl) piperazine 97%
  • 5g
  • $ 246.00
  • Sigma-Aldrich
  • 1-(3-Hydroxyphenyl) piperazine 97%
  • 1g
  • $ 74.00
  • Chemenu
  • 3-(Piperazin-1-yl)phenol 95%+
  • 5g
  • $ 41.00
  • Chemenu
  • 3-(Piperazin-1-yl)phenol 95%+
  • 25g
  • $ 140.00
  • American Custom Chemicals Corporation
  • 1-(3-Hydroxyphenyl) piperazine 95.00%
  • 25G
  • $ 1119.54
  • American Custom Chemicals Corporation
  • 1-(3-Hydroxyphenyl) piperazine 95.00%
  • 5G
  • $ 772.58
  • Alichem
  • 1-(3-Hydroxyphenyl) piperazine
  • 100g
  • $ 413.09
  • Alichem
  • 1-(3-Hydroxyphenyl) piperazine
  • 25g
  • $ 165.64
Total 43 raw suppliers
Chemical Property of 1-(3-Hydroxyphenyl)piperazine
Chemical Property:
  • Vapor Pressure:4.89E-06mmHg at 25°C 
  • Melting Point:217-221 ºC 
  • Boiling Point:371.3oC at 760 mmHg 
  • PKA:10.33±0.10(Predicted) 
  • Flash Point:178.3oC 
  • PSA:35.50000 
  • Density:1.141g/cm3 
  • LogP:1.19560 
  • Sensitive.:Air Sensitive 
  • XLogP3:0.8
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:1
  • Exact Mass:178.110613074
  • Heavy Atom Count:13
  • Complexity:157
Purity/Quality:

99%, *data from raw suppliers

1-(3-Hydroxyphenyl) piperazine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:Xn,C 
  • Statements: 22-37/38-41 
  • Safety Statements: 26-36/37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1CN(CCN1)C2=CC(=CC=C2)O
Technology Process of 1-(3-Hydroxyphenyl)piperazine

There total 5 articles about 1-(3-Hydroxyphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogen bromide; at 140 ℃; for 6h;
DOI:10.1248/cpb.49.1314
Guidance literature:
With boron tribromide; In dichloromethane; for 72h;
DOI:10.1016/j.tetlet.2004.07.131

Reference yield: 65.0%

Guidance literature:
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