1-AMINO-3-BUTENE HYDROCHLORIDE

Base Information

• Chemical Name: 1-AMINO-3-BUTENE HYDROCHLORIDE
• CAS No.: 17875-18-2
• Molecular Formula: C4H9 N . Cl H
• Molecular Weight: 107.583
• Hs Code.: 2921199090
• Mol file: 17875-18-2.mol

Synonyms:3-Butenylamine,hydrochloride (8CI); 3-Butenamine hydrochloride

Chemical Property of 1-AMINO-3-BUTENE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 78.5mmHg at 25°C
• Melting Point: 176-180 °C(lit.)
• Boiling Point: 82.5°C at 760 mmHg
• PSA: 26.02000
• LogP: 2.02350
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%, ^*data from raw suppliers

3-Butenylamine hydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-37/38-41-42/43
• Safety Statements: 22-26-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Butenylamine hydrochloride can be used to synthesize 2-(3-butenylamino)-3-chloronaphthalene-1,4-dione via reaction with 2,3-dichloro-1,4-naphthoquinone in the presence of sodium bicarbonate.

Technology Process of 1-AMINO-3-BUTENE HYDROCHLORIDE

There total 7 articles about 1-AMINO-3-BUTENE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(3-butenyl)phthalimide (52898-32-5) → but-3-en-1-amine hydrochloride (17875-18-2)

Guidance literature:

N-(3-butenyl)phthalimide; With hydrazine hydrate; In ethanol; at 50 ℃; for 1.03333h; Inert atmosphere;

With hydrogenchloride; In water; at 20 ℃; for 0.216667h;

DOI:10.1021/acs.joc.5b01301

Reference yield: 96.0%

homoalylic alcohol (627-27-0) → but-3-en-1-amine hydrochloride (17875-18-2)

Guidance literature:

homoalylic alcohol; With phthalimide; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 ℃; for 3h; Mitsunobu reaction;

With hydrazine; In ethanol; water; at 80 ℃;

DOI:10.3987/COM-05-S(T)65

Reference yield: 54.0%

C11H21BN(1-)*H(1+) → but-3-en-1-amine hydrochloride (17875-18-2)

Guidance literature:

With hydrogenchloride; formaldehyd; ammonia; In 1,4-dioxane; methanol; at 55 ℃; for 72h; Sealed tube;

DOI:10.1039/c8ob02152j

upstream raw materials:

4-azido-1-butene

1-buten-3

N-(3-butenyl)phthalimide

homoalylic alcohol

Downstream raw materials:

2-ethenyl-N-3-butenyl-benzeneethaneamine

2-ethenyl-4,5-dimethoxy-N-3-butenyl-benzenenemethanamine

2-ethenyl-4,5-dimethoxy-N-3-butenyl-benzeneethanamine

2-ethenyl-1-(phenylmethyl)-N-3-butenyl-1H-indole-3-ethanamine

Refernces

• 1、 Kuznetsov,Tikhov,Godovikov,Khrustalev,Bubnov. "New enolate-carbodiimide rearrangement in the concise synthesis of 6-amino-2,3-dihydro-4-pyridinones from homoallylamines". supporting information. p. 4283 - 4298. Retrieved 2016/05/24.
• 2、 Zawatzky, Kerstin,Kamuf, Matthias,Trapp, Oliver. "Chiral 1,2-dialkenyl diaziridines: Synthesis, enantioselective separation, and nitrogen inversion barriers". . p. 156 - 162. Retrieved 2015/03/04.