3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Base Information

Chemical Name:3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063
CAS No.:1425495-89-1
Molecular Formula:C₂₈H₃₅N₂O₆
Molecular Weight:495.596
Hs Code.:

Synonyms:3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Suppliers and Price of 3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

There total 4 articles about 3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 38632-29-0
1-Oxyl-1,2,5,6-tetrahydro-2,2,6,6-tetramethylpyridin-4-carboxylic acid radical

: 162705-07-9
3-amino-deoxycombretastatin A₄

: 1425495-89-1
3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Guidance literature:: 1-Oxyl-1,2,5,6-tetrahydro-2,2,6,6-tetramethylpyridin-4-carboxylic acid radical; 3-amino-deoxycombretastatin A₄; With dmap; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;

With dicyclohexyl-carbodiimide; In dichloromethane; for 24h; Inert atmosphere;
DOI:10.1016/j.bmc.2012.12.046

Reference yield:

: 31680-08-7
4-methoxy-3-nitrobenzaldehyde

: 1425495-89-1
3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic anhydride; triethylamine / 3 h / 140 °C

2.1: copper; quinoline / 2 h / 140 °C

3.1: acetic acid; zinc / 24 h / 20 °C

4.1: dmap / dichloromethane / 0.08 h / 20 °C / Inert atmosphere

4.2: 24 h / Inert atmosphere

With quinoline; dmap; acetic anhydride; copper; acetic acid; triethylamine; zinc; In dichloromethane;
DOI:10.1016/j.bmc.2012.12.046

Reference yield:

: 162705-13-7
(Z)-1-(4''-methoxy-3''-nitrophenyl)-2-(3',4',5'-trimethoxyphenyl)ethene

: 1425495-89-1
3'-N-(1-oxyl-2,2,6,6-tetramethyl-4-tetrahydropyridinylcarbonyl)-amido-AVE8063

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid; zinc / 24 h / 20 °C

2.1: dmap / dichloromethane / 0.08 h / 20 °C / Inert atmosphere

2.2: 24 h / Inert atmosphere

With dmap; acetic acid; zinc; In dichloromethane;
DOI:10.1016/j.bmc.2012.12.046