N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride

Base Information

• Chemical Name: N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride
• CAS No.: 367932-02-3
• Molecular Formula: C₂₁H₁₈N₄O₃S₂*ClH
• Molecular Weight: 474.992

Synonyms:N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride

Chemical Property of N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride

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Technology Process of N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride

There total 1 articles about N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethylene dichloride hydrochloride + 3-(4-cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxylic Acid Hydrochloride + 2-benzenesulfonyl-ethylamine Hydrochloride (38752-48-6) → N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride (367932-02-3)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;

Reference yield:

ethylene dichloride hydrochloride + N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride (367932-02-3) + 2-(phenylthio)ethanamine (2014-75-7) → N-(2-Phenylthio-1-ethyl)3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide Hydrochloride (367932-23-8)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;

Reference yield:

ethylene dichloride hydrochloride + N-(2-Phenylsulfonyl-1-ethyl)-3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide hydrochloride (367932-02-3) + 2-phenoxyethanamine (1758-46-9) → N-(2-Phenyloxy-1-ethyl)3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide Hydrochloride (367932-24-9)

Guidance literature:

With benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In N,N-dimethyl-formamide;

upstream raw materials:

2-benzenesulfonyl-ethylamine Hydrochloride

Downstream raw materials:

N-(2-Phenylthio-1-ethyl)3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide Hydrochloride

N-(2-Phenyloxy-1-ethyl)3-(4-Cyanophenyl)-2,3-dihydro-imidazo[2,1-b]thiazole-5-carboxamide Hydrochloride

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