4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Base Information

Chemical Name:4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide
CAS No.:217495-91-5
Molecular Formula:C₃₆H₃₁N₃O₂
Molecular Weight:537.661
Hs Code.:

Synonyms:4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Suppliers and Price of 4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

There total 5 articles about 4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 94-09-7
p-aminoethylbenzoate

: 217495-91-5
4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Guidance literature:: Multi-step reaction with 4 steps

1: 8.1 percent / WSC, HOBt / tetrahydrofuran / 240 h / Ambient temperature

2: 86 percent / 1 N NaOH / ethanol / 18 h / Ambient temperature

3: oxalyl chloride, DMF / CH₂Cl₂ / 1 h

4: Et₃N / tetrahydrofuran / 1 h

With sodium hydroxide; oxalyl dichloride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1248/cpb.46.1566

Reference yield:

: 168626-74-2
4-[([1,1'-Biphenyl]-2-carbonyl)amino]benzoic Acid

: 217495-91-5
4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl chloride, DMF / CH₂Cl₂ / 1 h

2: Et₃N / tetrahydrofuran / 1 h

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1248/cpb.46.1566

Reference yield:

: 217495-89-1
ethyl 4-([1,1'-biphenyl]-2-carboxamido)benzoate

: 217495-91-5
4'-(4-benzyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-1-carbonyl)-2-phenylbenzanilide

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / 1 N NaOH / ethanol / 18 h / Ambient temperature

2: oxalyl chloride, DMF / CH₂Cl₂ / 1 h

3: Et₃N / tetrahydrofuran / 1 h

With sodium hydroxide; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1248/cpb.46.1566