3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione

Base Information

• Chemical Name: 3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione
• CAS No.: 853649-57-7
• Molecular Formula: C₁₂H₉I₂NO₃
• Molecular Weight: 469.017
• Mol file: 853649-57-7.mol

Synonyms:3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione

Chemical Property of 3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione

There total 1 articles about 3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3,4-dibromo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione (205128-48-9) → 3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione (853649-57-7)

Guidance literature:

With acetic acid; sodium iodide; for 2h; Heating;

DOI:10.1016/j.tet.2005.03.016

Reference yield: 84.0%

3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione (853649-57-7) → 3,4-diiodo-2,5-dihydro-1-(4-hydroxybenzyl)-1H-pyrrole-2,5-dione (853649-58-8)

Guidance literature:

With boron tribromide; In dichloromethane; at -10 - 20 ℃; for 1.5h;

DOI:10.1016/j.tet.2005.03.016

Reference yield: 58.0%

3,4-diiodo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione (853649-57-7) + (5-(diethoxymethyl)furan-2-yl)boronic acid (378185-02-5) → 3,4-bis[5-(diethoxymethyl)fur-2-yl]-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione (853649-37-3)

Guidance literature:

With triethylamine; palladium on activated charcoal; In ethanol; for 24h; Heating;

DOI:10.1016/j.tet.2005.03.016

upstream raw materials:

3,4-dibromo-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione

Downstream raw materials:

3,4-diiodo-2,5-dihydro-1-(4-hydroxybenzyl)-1H-pyrrole-2,5-dione

3,4-bis[5-(diethoxymethyl)fur-2-yl]-2,5-dihydro-1-(4-methoxybenzyl)-1H-pyrrole-2,5-dione