7-Methyl-1-Indanone

Base Information

• Chemical Name: 7-Methyl-1-Indanone
• CAS No.: 39627-61-7
• Molecular Formula: C10H10O
• Molecular Weight: 146.189
• Hs Code.: 2914399090
• Mol file: 39627-61-7.mol

Synonyms:7-Methyl-indan-1-one;1-Indanone-7-carboxylic acid;7-methyl-2,3-dihydro-1H-inden-1-one;7-methlyindanone

Chemical Property of 7-Methyl-1-Indanone

Chemical Property:

• Vapor Pressure: 0.0123mmHg at 25°C
• Melting Point: 52-56 °C
• Refractive Index: 1.574
• Boiling Point: 260.4 ºCat 760 mmHg
• Flash Point: 107.2 ºC
• PSA: 17.07000
• Density: 1.113
• LogP: 2.12390
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

7-Methyl-1-indanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Methyl-1-Indanone

There total 36 articles about 7-Methyl-1-Indanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

3-oxo-2,3-dihydro-1H-inden-4-yl trifluoromethanesulfonate (868374-23-6) + dimethyl zinc(II) (544-97-8) → 7-methyl-1-indanone (39627-61-7)

Guidance literature:

With 1,3-bis[(diphenylphosphino)propane]dichloronickel(II); In tetrahydrofuran; toluene; at 20 ℃; for 12h;

DOI:10.1039/c1ob06780j

Reference yield: 92.0%

dimethyl 7-methyl-1-oxo-1,3-dihydro-2H-indene-2,2-dicarboxylate → 7-methyl-1-indanone (39627-61-7)

Guidance literature:

With sodium acetate; at 150 ℃; for 18h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.0c02986

Reference yield: 88.0%

diethyl 7-methyl-1-oxo-1,3-dihydro-2H-indene-2,2-dicarboxylate → 7-methyl-1-indanone (39627-61-7)

Guidance literature:

With 1,1,1,3',3',3'-hexafluoro-propanol; sodium acetate; at 150 ℃; for 18h; Inert atmosphere;

upstream raw materials:

7t-Methyl-(3arH,7atH)-3a,4,7,7a-tetrahydro-indanon-⁽¹⁾

3-(3-methylphenyl)propanoic acid

1-(2-methylphenyl)-2-propen-1-one

3-(3-methylphenyl)propionyl chloride

Downstream raw materials:

7-Methyl-indan-1-on-amidinohydrazon

2,3-Dihydro-2-(3-methoxy-5-methylbenzyliden)-7-methyl-1H-inden-1-on

4-methyl-1H-indene

(1S,2R)-(-)-cis-1-[(2R)-4-hydroxymethyl-2-phenyl-1,2,5,6-tetrahydropyridin-1-yl]-7-methylindan-2-ol