(E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone

Base Information

• Chemical Name: (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone
• CAS No.: 150981-43-4
• Molecular Formula: C₁₇H₁₁Cl₂N₃O
• Molecular Weight: 344.2

Synonyms:(E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone

Chemical Property of (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone

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Technology Process of (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone

There total 1 articles about (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

para-chloroacetophenone (99-91-2) + 2-(4-chlorophenyl)-2H-1,2,3-triazole-4-carbaldehyde (41886-24-2) → (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone (150981-43-4)

Guidance literature:

With sodium hydroxide; In ethanol; at 25 ℃; for 3h;

Reference yield: 85.0%

4-hydrazinobenzene-1-sulfonamide hydrochloride (17852-52-7,27918-19-0) + (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone (150981-43-4) → 4-{3-(4-Chloro-phenyl)-5-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-4,5-dihydro-pyrazol-1-yl}-benzenesulfonamide (150981-72-9)

Guidance literature:

In ethanol; for 4h; Heating;

Reference yield: 66.0%

phenylhydrazine hydrochloride (59-88-1) + (E)-1-(4-Chloro-phenyl)-3-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-propenone (150981-43-4) → 2-(4-Chloro-phenyl)-4-[5-(4-chloro-phenyl)-2-phenyl-3,4-dihydro-2H-pyrazol-3-yl]-2H-[1,2,3]triazole (150981-70-7)

Guidance literature:

In ethanol; for 4h; Heating;

upstream raw materials:

para-chloroacetophenone

2-(4-chlorophenyl)-2H-1,2,3-triazole-4-carbaldehyde

Downstream raw materials:

2-(4-Chloro-phenyl)-4-[5-(4-chloro-phenyl)-2-phenyl-3,4-dihydro-2H-pyrazol-3-yl]-2H-[1,2,3]triazole

4-{3-(4-Chloro-phenyl)-5-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-4,5-dihydro-pyrazol-1-yl}-benzenesulfonamide

4-{4-Bromo-3-(4-chloro-phenyl)-5-[2-(4-chloro-phenyl)-2H-[1,2,3]triazol-4-yl]-pyrazol-1-yl}-benzenesulfonamide

C₃₀H₂₃Cl₂N₇O₂S₂

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