(R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine

Base Information

• Chemical Name: (R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine
• CAS No.: 1174565-35-5
• Molecular Formula: C₂₁H₂₆ClNO
• Molecular Weight: 343.897
• Mol file: 1174565-35-5.mol

Synonyms:(R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine

Chemical Property of (R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of (R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine

There total 1 articles about (R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

(+)-(R)-2-(2-chloroethyl)-1-methylpyrrolidine hydrochloride (67499-71-2,56824-22-7) + 1-(4-chloro-phenyl)-1-phenyl-ethanol (59767-24-7) → (R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine (1174565-35-5)

Guidance literature:

With sodium amide; In toluene; for 8h; Reflux;

Reference yield:

(R)-2-[2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine (1174565-35-5) → clemestine

Guidance literature:

In ethanol; hexane; diethylamine; Resolution of racemate;

upstream raw materials:

(+)-(R)-2-(2-chloroethyl)-1-methylpyrrolidine hydrochloride

1-(4-chloro-phenyl)-1-phenyl-ethanol