N-(1-Methylethyl)-3-(1-naphthalenyloxy)-1-propanamine

Base Information

• Chemical Name: N-(1-Methylethyl)-3-(1-naphthalenyloxy)-1-propanamine
• CAS No.: 20875-54-1
• Molecular Formula: C16H21NO
• Molecular Weight: 243.34404
• Hs Code.: 2922299090
• DSSTox Substance ID: DTXSID60437570
• Nikkaji Number: J731.049H
• Wikidata: Q82253095
• ChEMBL ID: CHEMBL139737
• Mol file: 20875-54-1.mol

Synonyms:20875-54-1;N-(1-METHYLETHYL)-3-(1-NAPHTHALENYLOXY)-1-PROPANAMINE;3-naphthalen-1-yloxy-N-propan-2-ylpropan-1-amine;CHEMBL139737;Deshydroxypropranolol;SCHEMBL22354431;DTXSID60437570;BDBM50061966;FT-0760072;Isopropyl-[3-(naphthalen-1-yloxy)-propyl]-amine;3-[(Naphthalen-1-yl)oxy]-N-(propan-2-yl)propan-1-amine

Chemical Property of N-(1-Methylethyl)-3-(1-naphthalenyloxy)-1-propanamine

Chemical Property:

• PSA: 21.26000
• LogP: 3.99760
• XLogP3: 4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 243.162314293
• Heavy Atom Count: 18
• Complexity: 229

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)NCCCOC1=CC=CC2=CC=CC=C21

Technology Process of N-(1-Methylethyl)-3-(1-naphthalenyloxy)-1-propanamine

There total 3 articles about N-(1-Methylethyl)-3-(1-naphthalenyloxy)-1-propanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

α-naphthol (90-15-3) → Deoxypropranolol (20875-54-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaOEt, EtOH, (ii) /BRN= 605278/

DOI:10.1021/jm00312a003

Reference yield:

3-(naphthalen-1-yloxy)-propyl chloride (20875-51-8) + isopropylamine (75-31-0) → Deoxypropranolol (20875-54-1)

Guidance literature:

DOI:10.1021/jm00312a003

Reference yield:

→ Deoxypropranolol (20875-54-1)

Guidance literature:

Ditosylat, Amin;

upstream raw materials:

3-(naphthalen-1-yloxy)-propyl chloride

isopropylamine

α-naphthol