N-benzhydryl isobutyramide

Base Information

• Chemical Name: N-benzhydryl isobutyramide
• CAS No.: 10253-97-1
• Molecular Formula: C₁₇H₁₉NO
• Molecular Weight: 253.344
• Mol file: 10253-97-1.mol

Synonyms:N-benzhydryl isobutyramide

Chemical Property of N-benzhydryl isobutyramide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzhydryl isobutyramide

There total 3 articles about N-benzhydryl isobutyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

N-(tert-butylperoxy(phenyl)methyl)isobutyramide (1612225-98-5) + phenylmagnesium bromide (100-58-3) → N-benzhydryl isobutyramide (10253-97-1)

Guidance literature:

In diethyl ether; for 0.25h; Inert atmosphere; Cooling with ice;

DOI:10.1021/ol5012168

Reference yield: 75.0%

Isobutyronitrile (78-82-0) + Diphenylmethane (101-81-5) → N-benzhydryl isobutyramide (10253-97-1)

Guidance literature:

With manganese(III) triacetate dihydrate; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; at 90 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c7ob00512a

Reference yield: 45.0%

isobutyryl chloride (79-30-1) + Benzhydrylamine (91-00-9) → N-benzhydryl isobutyramide (10253-97-1)

Guidance literature:

With pyridine; In benzene; for 1h; Heating;

DOI:10.1007/BF00764709 DOI:10.1007/BF00769646

upstream raw materials:

isobutyryl chloride

Benzhydrylamine

N-(tert-butylperoxy(phenyl)methyl)isobutyramide

phenylmagnesium bromide