4-Methylthiazole-2-carbaldehyde

Base Information

Chemical Name:4-Methylthiazole-2-carbaldehyde
CAS No.:13750-68-0
Molecular Formula:C5H5NOS
Molecular Weight:127.167
Hs Code.:29341000
European Community (EC) Number:627-825-4
DSSTox Substance ID:DTXSID40401370
Nikkaji Number:J2.754.760E
Wikidata:Q72491173
Mol file:13750-68-0.mol

Synonyms:13750-68-0;4-Methylthiazole-2-carbaldehyde;4-Methyl-1,3-thiazole-2-carbaldehyde;4-Methyl-2-thiazolecarboxaldehyde;4-Methyl-1,3-thiazole-2-carboxaldehyde;4-Methyl-thiazole-2-carbaldehyde;2-THIAZOLECARBOXALDEHYDE, 4-METHYL-;MFCD00022450;4-Methyl-2-thiazole carboxaldehyde;4-METHYLTHIAZOLE-2-CARBOXALDEHYDE;SCHEMBL475763;DTXSID40401370;4-METHYL-2-FORMYLTHIAZOLE;NYMCQLLAIMUVSY-UHFFFAOYSA-N;4-methyl-2-thiazole-carboxaldehyde;AKOS011377070;CS-W011145;PB14084;PS-4373;4-Methyl-2-thiazolecarboxaldehyde, 97%;AM803186;BP-12649;SY014134;FT-0649701;EN300-79711;4-METHYL-2-THIAZOLECARBOXALDEHYDE 97;A807265;W-205503;Z1037606426

Suppliers and Price of 4-Methylthiazole-2-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-1,3-thiazole-2-carbaldehyde
250mg
$ 45.00

SynQuest Laboratories
4-Methyl-1,3-thiazole-2-carboxaldehyde
5 g
$ 272.00

SynQuest Laboratories
4-Methyl-1,3-thiazole-2-carboxaldehyde
250 mg
$ 24.00

SynQuest Laboratories
4-Methyl-1,3-thiazole-2-carboxaldehyde
1 g
$ 80.00

Sigma-Aldrich
4-Methyl-2-thiazolecarboxaldehyde 97%
1g
$ 54.50

Sigma-Aldrich
4-Methyl-2-thiazolecarboxaldehyde 97%
5g
$ 209.00

Matrix Scientific
4-Methyl-1,3-thiazole-2-carbaldehyde 97%
5g
$ 247.00

Crysdot
4-Methylthiazole-2-carbaldehyde 95+%
1g
$ 40.00

Crysdot
4-Methylthiazole-2-carbaldehyde 95+%
5g
$ 130.00

Crysdot
4-Methylthiazole-2-carbaldehyde 95+%
10g
$ 235.00

Total 37 raw suppliers

Chemical Property of 4-Methylthiazole-2-carbaldehyde

Chemical Property:

Vapor Pressure:0.074mmHg at 25°C
Refractive Index:n20/D 1.5600(lit.)
Boiling Point:236.008 °C at 760 mmHg
PKA:0.86±0.10(Predicted)
Flash Point:96.535 °C
PSA：58.20000
Density:1.183 g/cm³
LogP:1.26400
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:127.00918496
Heavy Atom Count:8
Complexity:96.4

Purity/Quality:

99% ^*data from raw suppliers

4-Methyl-1,3-thiazole-2-carbaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36-43
Safety Statements: 26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CSC(=N1)C=O
Uses 4-Methyl-1,3-thiazole-2-carbaldehyde is used to prepare selective cyclooxygenase-2 inhibitors. Thiazole containing compounds demonstrated excellent oral activity.

Technology Process of 4-Methylthiazole-2-carbaldehyde

There total 12 articles about 4-Methylthiazole-2-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 693-95-8
4-Methylthiazole

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 13750-68-0
4-methyl-thiazole-2-carbaldehyde

Guidance literature:: 4-Methylthiazole; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 3h;
DOI:10.1055/s-2008-1067147