5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Base Information

Chemical Name:5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one
CAS No.:104107-22-4
Molecular Formula:C₁₀H₉BrO
Molecular Weight:225.085
Hs Code.:2914700090
DSSTox Substance ID:DTXSID30564726
Mol file:104107-22-4.mol

Synonyms:104107-22-4;5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one;5-Bromo-2-methyl-1-indanone;5-BROMO-2-METHYL-INDAN-1-ONE;5-BROMO-2-METHYL-2,3-DIHYDROINDEN-1-ONE;2-methyl-5-bromo-1-indanone;SCHEMBL1500072;DTXSID30564726;GMWXCOYOQNIWPE-UHFFFAOYSA-N;AMY31531;MFCD13152125;AKOS015912043;SB30342;AS-47213;CS-0138770;F12673

Suppliers and Price of 5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromo-2-methyl-indan-1-one
100mg
$ 220.00

J&W Pharmlab
5-Bromo-2-methyl-indan-1-one 97%
50mg
$ 156.00

Crysdot
5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one 95+%
1g
$ 518.00

Chemenu
5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one 95%
1g
$ 489.00

Alichem
5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one
1g
$ 417.78

Total 15 raw suppliers

Chemical Property of 5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Chemical Property:

PSA：17.07000
LogP:2.82400
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:223.98368
Heavy Atom Count:12
Complexity:202

Purity/Quality:

97% ^*data from raw suppliers

5-Bromo-2-methyl-indan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(C1=O)C=CC(=C2)Br

Technology Process of 5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one

There total 5 articles about 5-Bromo-2-methyl-2,3-dihydro-1H-inden-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 34598-49-7
5-Bromo-1-indanone

: 104107-22-4
5-bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; water;

Reference yield:

: methyl 5-bromo-2-methyl-1-oxo-2,3-dihydro-1H-indene-2-carboxylate

: 104107-22-4
5-bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Guidance literature:: With hydrogenchloride; acetic acid; In water; at 100 ℃; for 16h;
DOI:10.1016/j.tet.2019.03.010

Reference yield:

: 628732-08-1
methyl 5-bromo-1-oxo-2,3-dihydro-1H-indene-2-carboxylate

: 104107-22-4
5-bromo-2-methyl-2,3-dihydro-1H-inden-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / dimethyl sulfoxide / 2 h / 23 °C / Inert atmosphere

2: hydrogenchloride; acetic acid / water / 16 h / 100 °C

With hydrogenchloride; potassium carbonate; acetic acid; In water; dimethyl sulfoxide;
DOI:10.1016/j.tet.2019.03.010