N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

Base Information

Chemical Name:N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine
CAS No.:1572439-47-4
Molecular Formula:C₁₉H₁₇FN₆
Molecular Weight:348.383
Hs Code.:

N<SUP>4</SUP>-(2,3-dimethyl-2H-indazol-6-yl)-N<SUP>2</SUP>-(4-fluorophenyl)pyrimidine-2,4-diamine

Synonyms:N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

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Technology Process of N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

There total 2 articles about N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 444731-74-2
N-(2-chloropyrimidin-4-yl)-2,3-dimethyl-2H-indazol-6-amine

: 371-40-4
4-fluoroaniline

: 1572439-47-4
N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

Guidance literature:: With hydrogenchloride; In water; isopropyl alcohol; at 85 ℃;
DOI:10.1111/cbdd.12243

Reference yield:

: 444731-72-0
2,3-dimethyl-6-amino-2H-indazole

: 1572439-47-4
N⁴-(2,3-dimethyl-2H-indazol-6-yl)-N²-(4-fluorophenyl)pyrimidine-2,4-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate / tetrahydrofuran; ethanol / 75 °C

2: hydrogenchloride / isopropyl alcohol; water / 85 °C

With hydrogenchloride; sodium hydrogencarbonate; In tetrahydrofuran; ethanol; water; isopropyl alcohol;
DOI:10.1111/cbdd.12243