3-(1-(Tert-butoxycarbonyl)piperidin-2-yl)propanoic acid

Base Information

• Chemical Name: 3-(1-(Tert-butoxycarbonyl)piperidin-2-yl)propanoic acid
• CAS No.: 669713-96-6
• Molecular Formula: C13H23NO4
• Molecular Weight: 257.33
• Hs Code.: 2933399990
• DSSTox Substance ID: DTXSID20373566
• Nikkaji Number: J2.843.843E
• Mol file: 669713-96-6.mol

Synonyms:669713-96-6;1-BOC-PIPERIDIN-2-YLPROPIONIC ACID;3-(1-(tert-butoxycarbonyl)piperidin-2-yl)propanoic acid;1-Boc-2-(2-Carboxyethyl)piperidine;3-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-2-yl]propanoic acid;3-[1-(TERT-BUTOXYCARBONYL)PIPERIDIN-2-YL]PROPANOIC ACID;2-(2-CARBOXYETHYL)PIPERIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;N-Boc-2-piperidinepropionic acid;MFCD02179009;3-(1-tert-butoxycarbonyl-2-piperidyl)propanoic acid;3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid;SCHEMBL3146378;3-[1-(tert-butoxycarbonyl)piperidin-2-yl]propionic acid;1-Boc-2-piperidinepropanoic acid;DTXSID20373566;BRQMDBOVDLUBAI-UHFFFAOYSA-N;1-boc-piperidin-2-ylpropiomic acid;CS-D0038;2-(2-Carboxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester;2-PIPERIDINEPROPANOIC ACID, 1-[(1,1-DIMETHYLETHOXY)CARBONYL]-;AKOS011499286;AB10978;AM101121;AS-37125;FT-0644827;EN300-61316;A13489;1-Boc-piperidin-2-ylpropiomic acid, AldrichCPR;Q-103045;3-[1-(tert-Butoxycarbonyl)piperidine-2-yl]propionic acid

Chemical Property of 3-(1-(Tert-butoxycarbonyl)piperidin-2-yl)propanoic acid

Chemical Property:

• Vapor Pressure: 4.83E-07mmHg at 25°C
• Refractive Index: 1.485
• Boiling Point: 386.4 °C at 760 mmHg
• PKA: 4.77±0.10(Predicted)
• Flash Point: 187.5 °C
• PSA: 66.84000
• Density: 1.102 g/cm³
• LogP: 2.57870
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 257.16270821
• Heavy Atom Count: 18
• Complexity: 309

Purity/Quality:

98% ^*data from raw suppliers

1-Boc-2-piperidinepropanoicacid 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)N1CCCCC1CCC(=O)O

Technology Process of 3-(1-(Tert-butoxycarbonyl)piperidin-2-yl)propanoic acid

There total 2 articles about 3-(1-(Tert-butoxycarbonyl)piperidin-2-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

cycl-isopropylidene malonate (2033-24-1) + tert-butyl 2-formylpiperidine-1-carboxylate (157634-02-1,132910-78-2) → 3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid (669713-96-6)

Guidance literature:

With formic acid; triethylamine; at 100 ℃;

DOI:10.1016/j.tetlet.2010.07.054

Reference yield:

(2E)-3-[1-(tert-butoxycarbonyl)piperidin-2-yl]-2-propenoic acid (741269-08-9) → 3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid (669713-96-6)

Guidance literature:

With hydrogen; palladium on activated carbon; In ethanol; at 20 ℃; for 22h;

Reference yield: 44.0%

3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid (669713-96-6) + (R)-2-phenyl-1-((3a5,45,65,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)ethanamine hydrochloride (178455-03-3) → tert-butyl 2-(2-[[(1R)-2-phenyl-1-[(1S,2S,6R,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]carbamoyl]ethyl)piperidine-1-carboxylate

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃;

upstream raw materials:

(2E)-3-[1-(tert-butoxycarbonyl)piperidin-2-yl]-2-propenoic acid

cycl-isopropylidene malonate

tert-butyl 2-formylpiperidine-1-carboxylate

Downstream raw materials:

3-[2]piperidyl-propionic acid ; hydrochloride

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 669713-96-6 2-(2-Carboxyethyl)piperidine-1-carboxylic acid tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send