2-Piperidinepropanoic acid, hydrochloride

Base Information

• Chemical Name: 2-Piperidinepropanoic acid, hydrochloride
• CAS No.: 99310-43-7
• Molecular Formula: C8H15NO2.ClH
• Molecular Weight: 193.674
• Hs Code.: 2933399090
• Mol file: 99310-43-7.mol

Synonyms:3-Piperidin-2-yl-propionic acid HCl;QC-3257;3-Piperidin-2-yl-propionicacid;RW3873;3-piperidin-2-yl-propionic acid hydrochloride;

Chemical Property of 2-Piperidinepropanoic acid, hydrochloride

Chemical Property:

• PSA: 49.33000
• LogP: 2.12410
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

3-(Piperidin-2-yl)propanoicacidhydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Piperidinepropanoic acid, hydrochloride

There total 4 articles about 2-Piperidinepropanoic acid, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 3-(pyridin-2-yl)acrylate (50610-14-5) → 3-[2]piperidyl-propionic acid ; hydrochloride (99310-43-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In tetrahydrofuran; chloroform; under 6000.6 Torr; Inert atmosphere;

Reference yield:

3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid (669713-96-6) → 3-[2]piperidyl-propionic acid ; hydrochloride (99310-43-7)

Guidance literature:

With hydrogenchloride; water; at 20 ℃; for 1h;

Reference yield:

3-(pyridin-2-yl)propanoic acid (15197-75-8) + pyrographite (7440-44-0) + phosphorous acid (10294-56-1) → 1-Hydroxy-3-(piperidin-2-yl)-propane-1,1-diphosphonic acid (116191-61-8) + 3-[2]piperidyl-propionic acid ; hydrochloride (99310-43-7)

Guidance literature:

With sodium hydroxide; anhydrous phosphorus trichloride; In hydrogenchloride; methanol; water;

upstream raw materials:

3-{1-[(tert-butoxy)carbonyl]piperidin-2-yl}propanoic acid

3-(pyridin-2-yl)propanoic acid

pyrographite

phosphorous acid

Downstream raw materials:

methyl 3-[1-(4-chloro-2,5-dimethyl-phenylsulfonyl)-piperidin-2-yl]-propionate

N-((1-(3-(1-(4-chloro-2,5-dimethylphenylsulfonyl)piperidin-2-yl)propanoyl)-4-(4-methylpiperazin-1-yl)piperidin-4-yl)methyl)acetamide

3-(1-(4-chloro-2,5-dimethylphenylsulfonyl)piperidin-2-yl)propionic acid ethyl ester

3-[1-(4-chloro-2,5-dimethyl-phenylsulfonyl)-piperidin-2-yl]-propionic acid

Refernces

• 1、 -. "TRICYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE". Page/Page column 44. . Retrieved 2010/02/14.