Methyl N-P-toluenesulfonyl-L-2-phenylglycinate

Base Information

Chemical Name:Methyl N-P-toluenesulfonyl-L-2-phenylglycinate
CAS No.:111047-54-2
Molecular Formula:C16H17 N O4 S
Molecular Weight:319.381
Hs Code.:
DSSTox Substance ID:DTXSID90427661
Nikkaji Number:J2.617.909B
Wikidata:Q82240313
Mol file:111047-54-2.mol

Synonyms:111047-54-2;METHYL N-P-TOLUENESULFONYL-L-2-PHENYLGLYCINATE;(S)-Methyl 2-(4-methylphenylsulfonamido)-2-phenylacetate;methyl (2S)-2-[(4-methylphenyl)sulfonylamino]-2-phenylacetate;Methyl (2S)-{[(4-methylphenyl)sulfonyl]amino}(phenyl)acetate;DTXSID90427661;RUYIDMOVZKCDIJ-HNNXBMFYSA-N;methyl (2S)-2-(4-methylbenzenesulfonamido)-2-phenylacetate;MFCD09261406;AKOS016842398;A894810;J-521848;(2S)-2-(Tosylamino)-2-phenylacetic acid methyl ester;Methyl (2S)-[(4-methylbenzene-1-sulfonyl)amino](phenyl)acetate;Benzeneacetic acid,a-[[(4-methylphenyl)sulfonyl]amino]-,methyl ester,(as)-;(S)-Phenyl-(toluene-4-sulfonylamino)-acetic acid methyl ester (Tos-L-Phg-OMe)

Suppliers and Price of Methyl N-P-toluenesulfonyl-L-2-phenylglycinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Methyl2-(4-methylphenylsulfonamido)-2-phenylacetate 97%
25g
$ 473.00

American Custom Chemicals Corporation
(S)-PHENYL-(TOLUENE-4-SULFONYLAMINO)-ACETIC ACID METHYL ESTER 95.00%
1G
$ 172.20

Total 20 raw suppliers

Chemical Property of Methyl N-P-toluenesulfonyl-L-2-phenylglycinate

Chemical Property:

Vapor Pressure:3.92E-09mmHg at 25°C
Melting Point:131-133 °C
Boiling Point:473.5°Cat760mmHg
PKA:8.96±0.50(Predicted)
Flash Point:240.1°C
PSA：80.85000
Density:1.256g/cm³
LogP:3.65930
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:319.08782920
Heavy Atom Count:22
Complexity:457

Purity/Quality:

97% ^*data from raw suppliers

(S)-Methyl2-(4-methylphenylsulfonamido)-2-phenylacetate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC(C2=CC=CC=C2)C(=O)OC
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N[C@@H](C2=CC=CC=C2)C(=O)OC

Technology Process of Methyl N-P-toluenesulfonyl-L-2-phenylglycinate

There total 55 articles about Methyl N-P-toluenesulfonyl-L-2-phenylglycinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: (Z)-methyl 2-phenyl-2-(tosylimino)acetate

: 111047-54-2
(S)-methyl 2-((4-methylphenyl)sulfonamido)-2-phenylacetate

Guidance literature:: With (R,R)-(?)-2,3-bis(t-butylmethylphosphino)quinoxaline; hydrogen; palladium diacetate; In 2,2,2-trifluoroethanol; at 20 ℃; for 24h; under 750.075 Torr; enantioselective reaction; Autoclave;
DOI:10.1021/acs.orglett.9b03452

Reference yield: 94.0%

: 19883-41-1,13226-98-7
D-phenylglycine methyl ester hydrochloride

: 98-59-9
p-toluenesulfonyl chloride

: 111047-53-1,1233-56-3,111047-54-2,148152-51-6
(R)-2-phenylglycine methyl ester hydrochloride salt

Guidance literature:: D-phenylglycine methyl ester hydrochloride; With sodium hydrogencarbonate; In tetrahydrofuran; ethyl acetate; at 20 ℃; for 0.333333h;

p-toluenesulfonyl chloride; In tetrahydrofuran; ethyl acetate; at 20 ℃; for 15h;
DOI:10.1021/op050182n

Reference yield: 90.0%

: 111047-52-0
methyl N-p-toluenesulfonyl-1-imino-1-phenylacetate

: 111047-53-1,111047-54-2,148152-51-6,1233-56-3
methyl 2-((4-methylphenyl)sulfonamido)-2-phenylacetate

Guidance literature:: With aluminium trichloride; diphenylsilane; In dichloromethane; at 20 ℃; for 11h; other Lewis acids, times and temperatures;
DOI:10.1246/bcsj.63.2588