(2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid

Base Information

• Chemical Name: (2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid
• CAS No.: 924283-69-2
• Molecular Formula: C₁₉H₂₃NO₃
• Molecular Weight: 313.397
• Mol file: 924283-69-2.mol

Synonyms:(2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid

Chemical Property of (2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid

There total 1 articles about (2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3R,1''S)-3-methyl-4-oxo-4-phenyl-2-[(1''-phenylethyl)-amino]butanoic acid (924283-63-6) → (2S,3R,4S,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid + (2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid (924283-69-2)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 5 ℃; for 0.5h; Title compound not separated from byproducts.;

DOI:10.1039/b613103d

Reference yield:

(2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid (924283-69-2) → (2S,3R,4S)-2-amino-4-hydroxy-3-methyl-4-phenylbutanoic acid + (2S,3R,4R)-2-amino-4-hydroxy-3-methyl-4-phenylbutanoic acid

Guidance literature:

With hydrogen bromide; hydrogen; palladium on activated charcoal; In methanol; water; at 25 ℃; under 836.056 Torr; Title compound not separated from byproducts.;

DOI:10.1039/b613103d

Reference yield:

(2S,3R,4R,1''S)-4-hydroxy-3-methyl-4-phenyl-2-[(1''-phenylethyl)amino]butanoic acid (924283-69-2) → (3S,4R,5S,1''S)-4-methyl-5-phenyl-3-(1''-phenylethylamino)-dihydrofuran-2(3H)-one hydrochloride + (3S,4R,5R,1''S)-4-methyl-5-phenyl-3-(1''-phenylethylamino)-dihydrofuran-2(3H)-one hydrochloride

Guidance literature:

With hydrogenchloride; In methanol; at 40 ℃; for 24h;

DOI:10.1039/b613103d

upstream raw materials:

(2S,3R,1''S)-3-methyl-4-oxo-4-phenyl-2-[(1''-phenylethyl)-amino]butanoic acid