C₄₄H₆₀N₈O₈

Base Information

• Chemical Name: C₄₄H₆₀N₈O₈
• CAS No.: 1449685-16-8
• Molecular Formula: C₄₄H₆₀N₈O₈
• Molecular Weight: 829.009
• Mol file: 1449685-16-8.mol

Synonyms:C₄₄H₆₀N₈O₈

Chemical Property of C₄₄H₆₀N₈O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₄H₆₀N₈O₈

There total 3 articles about C₄₄H₆₀N₈O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate (811442-84-9) + Hoechst 33258 acid → C44H60N8O8 (1449685-16-8)

Guidance literature:

Hoechst 33258 acid; With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1021/ja4046907

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C44H60N8O8 (1449685-16-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C

2.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 20 °C

2.2: 2 h / 20 °C

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja4046907

Reference yield:

1,14-diamino-3,6,9,12-tetraoxatetradecane (68960-97-4,892154-56-2) → C44H60N8O8 (1449685-16-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C

2.1: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 20 °C

2.2: 2 h / 20 °C

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ja4046907

upstream raw materials:

tert-butyl N-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethyl]carbamate

di-tert-butyl dicarbonate

1,14-diamino-3,6,9,12-tetraoxatetradecane

Downstream raw materials:

C₇₇H₉₇N₉O₁₆