2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone

Base Information

Chemical Name:2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone
CAS No.:126581-65-5
Molecular Formula:C8H6BrFO2
Molecular Weight:233.037
Hs Code.:2914700090
European Community (EC) Number:623-935-1
DSSTox Substance ID:DTXSID70381171
Wikidata:Q82171830
Mol file:126581-65-5.mol

Synonyms:2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone;126581-65-5;2-Bromo-5'-fluoro-2'-hydroxyacetophenone;5-Fluoro-2-hydroxyphenacyl bromide;Ethanone, 2-bromo-1-(5-fluoro-2-hydroxyphenyl)-;SCHEMBL3230200;DTXSID70381171;MFCD03094564;AKOS015912042;PS-9979;CS-0196647;FT-0643053;E73912;2-bromo-1-(5-fluoro-2-hydroxy-phenyl)ethanone;2-Bromo-5'-fluoro-2'-hydroxyacetophenone, 97%;A805572;J-005401

Suppliers and Price of 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone
100mg
$ 75.00

SynQuest Laboratories
5-Fluoro-2-hydroxyphenacyl bromide
1 g
$ 45.00

SynQuest Laboratories
5-Fluoro-2-hydroxyphenacyl bromide
5 g
$ 138.00

Sigma-Aldrich
2-Bromo-5′-fluoro-2′-hydroxyacetophenone 97%
5g
$ 275.00

Sigma-Aldrich
2-Bromo-5′-fluoro-2′-hydroxyacetophenone 97%
1g
$ 80.40

Heterocyclics
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone 97%
5g
$ 106.00

Heterocyclics
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone 97%
25g
$ 328.00

Crysdot
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone 97%
25g
$ 621.00

Biosynth Carbosynth
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone
25 g
$ 761.50

Biosynth Carbosynth
2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone
1 g
$ 69.70

Total 21 raw suppliers

Chemical Property of 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone

Chemical Property:

Vapor Pressure:0.00118mmHg at 25°C
Melting Point:87-91 °C
Refractive Index:1.585
Boiling Point:290.6 °C at 760 mmHg
PKA:7.50±0.43(Predicted)
Flash Point:129.5 °C
PSA：37.30000
Density:1.703 g/cm³
LogP:2.10890
Storage Temp.:Keep Cold
Sensitive.:Lachrymatory
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:231.95352
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn,C
Hazard Codes:Xn,C
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)C(=O)CBr)O

Technology Process of 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone

There total 3 articles about 2-Bromo-1-(5-fluoro-2-hydroxyphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

: 126581-65-5
α-bromo-(2-hydroxy-5-fluoro)acetophenone

Guidance literature:

Reference yield: 80.0%

: 394-32-1
1-(5-fluoro-2-hydroxyphenyl)ethan-1-one

: 126581-65-5
α-bromo-(2-hydroxy-5-fluoro)acetophenone

Guidance literature:: With bromine; In 1,4-dioxane; diethyl ether;
DOI:10.1007/BF00764715

Reference yield:

: 459-60-9
1-fluoro-4-methoxybenzene

: 126581-65-5
α-bromo-(2-hydroxy-5-fluoro)acetophenone

Guidance literature:: Multi-step reaction with 2 steps

1: 44.1 percent / aluminum trichloride / CCl₄

2: 80 percent / bromine / diethyl ether; dioxane

With aluminium trichloride; bromine; In 1,4-dioxane; tetrachloromethane; diethyl ether;
DOI:10.1007/BF00764715