4-(Pentafluorosulfur)benzyl alcohol

Base Information

• Chemical Name: 4-(Pentafluorosulfur)benzyl alcohol
• CAS No.: 773872-73-4
• Molecular Formula: C₇H₇F₅OS
• Molecular Weight: 234.19
• Hs Code.: 2905599890
• Mol file: 773872-73-4.mol

Synonyms:[4-(pentafluoro-λ⁶-sulfanyl)phenyl]methanol

Chemical Property of 4-(Pentafluorosulfur)benzyl alcohol

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-(Pentafluorosulfur)benzyl alcohol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(Pentafluorosulfur)benzyl alcohol

There total 2 articles about 4-(Pentafluorosulfur)benzyl alcohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-(pentafluoro- λ6-sulfanyl)benzaldehyde (401892-84-0) → [4-(pentafluoro-λ6-sulfanyl)phenyl]methanol (773872-73-4)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.tetlet.2016.12.056

Reference yield: 81.0%

4-(pentafluoro-λ6-sulphanyl)benzoic acid (832-32-6) → [4-(pentafluoro-λ6-sulfanyl)phenyl]methanol (773872-73-4) + 4-mercaptobenzyl alcohol (53339-53-0)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at -5 - 20 ℃;

Reference yield: 77.0%

para-xylene (106-42-3) + [4-(pentafluoro-λ6-sulfanyl)phenyl]methanol (773872-73-4) → 1-(4-(pentafluorothio)benzyl)-2,5-dimethylbenzene

Guidance literature:

With hexafluoro antimony(V)acid hexahydrate; at 80 ℃; for 48h; Sealed tube;

DOI:10.1002/anie.201612573

upstream raw materials:

4-(pentafluoro-λ⁶-sulphanyl)benzoic acid

4-(pentafluoro- λ⁶-sulfanyl)benzaldehyde

Downstream raw materials:

1-(bromomethyl)-4-(pentafluoro-λ⁶-sulfanyl)benzene

Refernces

• 1、 -. "Novel phenyl-substituted imidazolidines, process for preparation thereof, medicaments comprising said compounds and use thereof". Page/Page column 38. . Retrieved 2011/08/04.