2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione

Base Information

• Chemical Name: 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione
• CAS No.: 1330776-76-5
• Molecular Formula: C₂₃H₂₄O₄
• Molecular Weight: 364.441
• Mol file: 1330776-76-5.mol

Synonyms:2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione

Chemical Property of 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione

There total 25 articles about 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3-hydroxy-5,5-dimethyl-2-(1',3'-diphenyl-1'-oxopropan-3'-yl)cyclohex-2-en-1-one + 1-(p-chlorophenyl)ethyl alcohol (3391-10-4) → 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione (1330776-76-5) + para-chloroacetophenone (99-91-2)

Guidance literature:

With oxygen; In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1055/s-0031-1289907

Reference yield: 67.0%

3-hydroxy-5,5-dimethyl-2-(1',3'-diphenyl-1'-oxopropan-3'-yl)cyclohex-2-en-1-one + C23H26OSi (1359950-48-3) → 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione (1330776-76-5) + (tert-butyldiphenylsilyl)(phenyl)methanone (1359950-53-0)

Guidance literature:

With oxygen; In 1,2-dichloro-ethane; at 20 ℃; for 36h;

DOI:10.1055/s-0031-1289907

Reference yield: 60.0%

3-hydroxy-5,5-dimethyl-2-(1',3'-diphenyl-1'-oxopropan-3'-yl)cyclohex-2-en-1-one + 1-[4-nitrophenyl]-1-ethanol (6531-13-1) → 2-hydroxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione (1330776-76-5) + (4-nitrophenyl)ethanone (100-19-6)

Guidance literature:

With oxygen; In 1,2-dichloro-ethane; at 20 ℃;

DOI:10.1055/s-0031-1289907

upstream raw materials:

2-hydroxyperoxy-5,5-dimethyl-2-(3-oxo-1,3-diphenylpropyl)cyclohexane-1,3-dione

dimedone

benzalacetophenone

(tert-butyldiphenylsilyl)(m-tolyl)methanol