C₉H₈ClIN₂O₂

Base Information

• Chemical Name: C₉H₈ClIN₂O₂
• CAS No.: 1227753-39-0
• Molecular Formula: C₉H₈ClIN₂O₂
• Molecular Weight: 338.532
• Mol file: 1227753-39-0.mol

Synonyms:C₉H₈ClIN₂O₂

Chemical Property of C₉H₈ClIN₂O₂

Chemical Property:

Purity/Quality:

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Technology Process of C₉H₈ClIN₂O₂

There total 1 articles about C₉H₈ClIN₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

methyl 2-chloroacetoacetate (4755-81-1,935731-92-3) + 2-iodophenylamine (615-43-0) → C9H8ClIN2O2 (1227753-39-0)

Guidance literature:

2-iodophenylamine; With hydrogenchloride; sodium nitrite; In methanol; water; Cooling;

methyl 2-chloroacetoacetate; With sodium acetate; In methanol; water; at 20 ℃; pH=5; Cooling;

DOI:10.3987/COM-10-11905

Reference yield: 74.0%

C9H8ClIN2O2 (1227753-39-0) + phenylacetylene (536-74-3) → 1-(2-iodophenyl)-3-methoxycarbonyl-5-phenylpyrazole

Guidance literature:

With triethylamine; copper(l) chloride; In dichloromethane; at 20 ℃; for 0.583333h; regioselective reaction;

DOI:10.3987/COM-20-14268

Reference yield: 56.0%

C9H8ClIN2O2 (1227753-39-0) + allyl alcohol (107-18-6) → C12H13IN2O3 (1227753-44-7) + C12H13IN2O3 (1227753-41-4)

Guidance literature:

With silver carbonate; In ethyl acetate; at 20 ℃; for 60h; Darkness;

DOI:10.3987/COM-10-11905

upstream raw materials:

methyl 2-chloroacetoacetate

2-iodophenylamine

Downstream raw materials:

C₁₂H₁₃IN₂O₃

C₁₂H₁₃IN₂O₃